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Polymer nanoparticles containing essential oils: new options for mosquito control

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Abstract

Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and social disability worldwide. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs. Therefore, the development of eco-friendly control tools is an important public health challenge. In this study, two different essential oils (EO) (geranium, Geranium maculatum, and bergamot, Citrus bergamia) loaded polymeric nanoparticle (PN) were elaborated using polyethylene glycol (PEG) and chitosan (Qx) as the polymeric matrix/coating. In addition, the mosquito larvicidal acute and residual activity of the PN was evaluated on Culex pipiens pipiens. The physicochemical characterization of PN revealed that PEG-PN had sizes <255 nm and encapsulation efficiency between 68 and 77%; Qx-PN showed sizes <535 nm and encapsulation efficiency between 22 and 38%. From the toxicological test, it was observed that Qx-PN produced higher acute and residual activity than PEG-PN. Overall, this study highlights that polymer nanoparticles containing essential oil are a promising source of eco-friendly mosquito larvicidal products.

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Acknowledgements

The authors gratefully acknowledge Universidad Nacional del Sur and CONICET (Consejo Nacional de Investigaciones Científicas y Técnicas) for the financial support.

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  1. FIA Laboratory, Analytical Chemistry Section, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253 (B8000CPB), Bahía Blanca, Buenos Aires, Argentina

    Jorge Omar Werdin González & Beatriz Fernández Band

  2. Laboratorio de Zoología de Invertebrados II, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, San Juan 670 (B8000CPB), Bahía Blanca, Buenos Aires, Argentina

    Jorge Omar Werdin González & Cristhian Alan Yeguerman

  3. Laboratorio de Zoología de Invertebrados II, INBIOSUR-CONICET, San Juan 670 (B8000CPB), Bahía Blanca, Buenos Aires, Argentina

    Emiliano Nicolás Jesser & Adriana Alicia Ferrero

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  1. Jorge Omar Werdin González
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Werdin González, J.O., Jesser, E.N., Yeguerman, C.A. et al. Polymer nanoparticles containing essential oils: new options for mosquito control. Environ Sci Pollut Res 24, 17006–17015 (2017). https://doi.org/10.1007/s11356-017-9327-4

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