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Partial Splenic Embolization in Myelodysplastic Syndrome Associated with Immune Thrombocytopenia

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Abstract

Backround: Currently, all treatments for patients with myelodysplastic syndrome (MDS) are still experimental. Supportive care, including treatment of infection and transfusion of blood and blood-related products, remains the most important aspect of therapy in these cases. This article discusses the results of partial splenic embolization in a patient who had MDS with refractory anemia.

Methods: The patient was placed under observation and was given supportive treatment. In addition to MDS with refractory anemia, there were management difficulties related to severe thrombocytopenia after alloimmunization from multiple blood transfusions. Therefore it is thought that partial splenic embolization might be an alternative treatment for the management thrombocytopenia.

Results: Although the patient did not live long because of the sepsis and ileus, hematologic response was obtained.

Conclusion: The observation during the treatment in this case suggests that partial splenic embolization may be a valid new alternative for treating thrombocytopenia due to alloimmunization.

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Authors and Affiliations

  1. Division of Hematology, Department of Internal Medicine, Adana Teaching and Medical Research Center, Baskent University Faculty of Medicine, Adana, Turkey

    Hakan Ozdogu MD, Can Boga MD & Ebru Kı zı lkı lı c MD

  2. Department of Radiology, Adana Teaching and Medical Research Center, Baskent University Faculty of Medicine, Adana, Turkey

    Levent Oğuzkurt MD

  3. Ziyapasa Caddesi, Kurtulus Mahallesi, Sinasi Efendi sokak, Dr. Ihsan Cerci, Apartmani. 7/25, Adana, Turkey

    Can Boga MD

Authors
  1. Hakan Ozdogu MD
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  2. Can Boga MD
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  3. Levent Oğuzkurt MD
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  4. Ebru Kı zı lkı lı c MD
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Correspondence to Can Boga MD.

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Ozdogu, H., Boga, C., Oğuzkurt, L. et al. Partial Splenic Embolization in Myelodysplastic Syndrome Associated with Immune Thrombocytopenia. J Thromb Thrombolysis 18, 213–216 (2004). https://doi.org/10.1007/s11239-005-0349-2

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  • DOI: https://doi.org/10.1007/s11239-005-0349-2

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