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Synthesis of cyclopropane-1,1,2,2-tetracarboxylic acid derivatives from aldehydes and CH-acids in the K2CO3/Bun 4NPF6/toluene heterogeneous system

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Abstract

A one-pot method for the synthesis of cyclopropane-1,1,2,2-tetracarboxylic derivatives was developed starting from aldehydes and cyanoacetic and 2-bromomalonic esters under heterogeneous conditions (K2CO3/PhMe) in the presence of recoverable phase-transfer catalyst Bun 4NPF6.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    G. V. Kryshtal, G. M. Zhdankina & S. G. Zlotin

Authors
  1. G. V. Kryshtal
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  2. G. M. Zhdankina
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  3. S. G. Zlotin
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Correspondence to S. G. Zlotin.

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Dedicated to Academician of the Russian Academy of Sciences O. M. Nefedov on the occasion of his 80th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2244–2247, November, 2011.

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Kryshtal, G.V., Zhdankina, G.M. & Zlotin, S.G. Synthesis of cyclopropane-1,1,2,2-tetracarboxylic acid derivatives from aldehydes and CH-acids in the K2CO3/Bun 4NPF6/toluene heterogeneous system. Russ Chem Bull 60, 2286–2290 (2011). https://doi.org/10.1007/s11172-011-0349-7

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  • DOI: https://doi.org/10.1007/s11172-011-0349-7

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