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Concentration of Bioactive Compounds from Elderberry (Sambucus nigra L.) Juice by Nanofiltration Membranes

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Abstract

For the first time the chemical profile, physico-chemical parameters, inhibition of carbohydrate hydrolysing enzymes associated with type 2 diabetes, and radical scavenging properties of Sambucus nigra L. (elderberry) juice treated by nanofiltration (NF) were investigated. Three commercial NF membranes with different molecular weight cut-off (MWCO) (400 and 1000 Da) and polymeric material (composite fluoro-polymer and polyethersulphone) were tested. According to HPLC analyses, most part of bioactive compounds were retained by the NF membranes producing a retentate fraction of interest for the production of functional foods. The NP030 membrane, a polyethersulphone membrane with a MWCO of 400 Da, exhibited the highest rejection towards phenolic compounds when compared with the other selected membranes. Accordingly, the produced retentate fractions exhibited the highest radical scavenging activity.

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Abbreviations

ABTS:

2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)

DPPH:

2,2-Diphenyl-1-picrylhydrazyl

IC50 :

Half maximal inhibitory concentration

MWCO:

Molecular weight cut-off

NF:

Nanofiltration

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Authors and Affiliations

  1. Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende (CS), Italy

    Rosa Tundis, Monica R. Loizzo & Marco Bonesi

  2. Department of Agricultural Science, Mediterranean University of Reggio Calabria, Via Graziella, Feo di Vito, 89123, Reggio Calabria, Italy

    Vincenzo Sicari

  3. Italian National Research Council (ITM-CNR), Institute on Membrane Technology, via Pietro Bucci, 17/C, 87036, Rende (CS), Italy

    Claudia Ursino, Ilaria Manfredi, Carmela Conidi, Alberto Figoli & Alfredo Cassano

Authors
  1. Rosa Tundis
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  2. Monica R. Loizzo
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  3. Marco Bonesi
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  4. Vincenzo Sicari
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  5. Claudia Ursino
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  8. Alberto Figoli
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  9. Alfredo Cassano
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Corresponding authors

Correspondence to Monica R. Loizzo or Alberto Figoli.

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The authors declare no conflict of interest. This article does not contain any studies with human or animal subjects.

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Tundis, R., Loizzo, M.R., Bonesi, M. et al. Concentration of Bioactive Compounds from Elderberry (Sambucus nigra L.) Juice by Nanofiltration Membranes. Plant Foods Hum Nutr 73, 336–343 (2018). https://doi.org/10.1007/s11130-018-0686-x

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  • DOI: https://doi.org/10.1007/s11130-018-0686-x

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