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Non-terpenoid biotransformations by Mucor species

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Abstract

Biotransformation is an important tool for the structural modification of organic compounds, especially natural products with complex structures, which are difficult to achieve using ordinary methods. It is also useful as a model for mammalian metabolism due to similarities between mammalian and microbial enzyme systems. The development of novel biocatalytic methods is a continuously growing area of chemistry, microbiology, and genetic engineering, and novel microorganisms and/or their enzymes are being screened intensively. This review covers the transformation of non-terpenoid compounds such as steroids, coumarins, flavonoids, drugs, pesticides and others by Mucor spp. up to the end of 2012.

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  1. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Avenida do Café, s/n, Ribeirão Prêto, São Paulo, 14040-903, Brazil

    Eliane de Oliveira Silva & Niege Araçari Jacometti Cardoso Furtado

  2. Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus Río San Pedro, 11510, Puerto Real, Cádiz, Spain

    Josefina Aleu & Isidro González Collado

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  1. Eliane de Oliveira Silva
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  2. Niege Araçari Jacometti Cardoso Furtado
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  3. Josefina Aleu
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  4. Isidro González Collado
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Correspondence to Josefina Aleu or Isidro González Collado.

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Silva, E.d.O., Furtado, N.A.J.C., Aleu, J. et al. Non-terpenoid biotransformations by Mucor species. Phytochem Rev 14, 745–764 (2015). https://doi.org/10.1007/s11101-014-9374-0

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