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Drug-related problems in Parkinson’s disease: the role of community pharmacists in primary care

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Abstract

Objective Although Parkinson’s disease is a common disorder in the elderly, there have been very few studies of the role of the pharmaceutical care services in detecting and reducing problems associated with drug treatment in community settings. The aim of this study was therefore to investigate the type and frequency of drug-related problems identified in patients with Parkinson’s disease by community pharmacists over an 8-month period and to assess the pharmaceutical service interventions, the type and frequency of intervention outcomes and the clinical benefits for the patients. Setting Community pharmacies in Germany. Method Thirty-two community pharmacists recruited 113 outpatients with idiopathic Parkinson’s disease who were receiving anti-Parkinsonian medication. Main outcome measure Drug-related problems. Results A total of 331 drug-related problems were identified by the pharmacists. Patients not receiving a medication, despite the presence of an indication or symptom, accounted for the highest proportion of drug-related problems (26.3%). The pharmacists proposed a total of 474 interventions, the most common of which was giving the patient treatment advice (19.6%). Intervention outcomes were recorded for 215 of the 331 drug-related problems, for which there were 553 individual outcome results. Adjustments of the drug regimen accounted for the highest percentage of individual results (43.6%). Conclusion Structured pharmaceutical care processes by community pharmacists have the potential to make a valuable contribution to health care and enhance the health outcomes of patients with Parkinson’s disease.

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Acknowledgments

The authors would also like to thank: the 32 study pharmacists for participation in the study; the 32 neurologists for participation in a survey on DRPs and unmet medical needs in Parkinson’s disease; and the members of the expert panel for the assessment of the clinical significance of DRPs and the seriousness and unexpectedness of adverse events; and Jane Irons and Mark Hickery for their assistance in editing the final manuscript.

Funding

The study was supported by an unrestricted grant from Solvay Pharmaceuticals GmbH, Hanover, Germany.

Conflicts of interests

None of the authors has any declarable conflict of interest.

Author information

Authors and Affiliations

  1. Institute for Biostatistics and Clinical Epidemiology, Charité University Medicine, CCM, Berlin, Germany

    Peter Martus

  2. Department of Neurology, University Hospital, Lund, Sweden

    Per Odin

  3. Department of Neurology, Central Hospital, Bremerhaven, Germany

    Per Odin

  4. Institute of Clinical Pharmacology, Charité University Medicine, CCM, Invalidenstrasse 115, 10115, Berlin, Germany

    Sabrina Schröder & Marion Schaefer

Authors
  1. Sabrina Schröder
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  2. Peter Martus
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  3. Per Odin
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  4. Marion Schaefer
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Correspondence to Sabrina Schröder.

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Schröder, S., Martus, P., Odin, P. et al. Drug-related problems in Parkinson’s disease: the role of community pharmacists in primary care. Int J Clin Pharm 33, 674–682 (2011). https://doi.org/10.1007/s11096-011-9526-x

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  • DOI: https://doi.org/10.1007/s11096-011-9526-x

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