The new coordination polymer silver bis(citrato)germanate was synthesized and exhibited pronounced antiviral activity against human influenza virus strains A/Hong Kong/1/68 (H3N2) and A/Puerto Rico/34 (H1N1). Its effective dose was five times lower than that of the reference drug oseltamivir, which made this compound promising for further studies in animal models.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 4, pp. 10 – 10, April, 2019.
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Seifullina, I.I., Martsinko, E.É., Gridina, T.L. et al. Antiviral Properties of the New Coordination Compound Silver Bis(Citrato)Germanate. Pharm Chem J 53, 318–321 (2019). https://doi.org/10.1007/s11094-019-01999-w
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DOI: https://doi.org/10.1007/s11094-019-01999-w