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Suspension based on calcium carbonate and sodium hyaluronate for the prevention and treatment of bone diseases

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Pharmaceutical Chemistry Journal Aims and scope

A combined drug based on natural calcium carbonate and sodium hyaluronate was developed for the prevention and treatment of bone diseases. A modified Dische method was proposed for the analysis of sodium hyaluronate in the presence of fructose in the complex dosage form. Quantitative analytical chemical techniques for determining sodium hydrogen phosphate, potassium dihydrogen phosphate, and excipients (fructose and methylparaben) in the drug suspension were developed.

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Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, Nizhnii Novgorod State Medical Academy, Nizhnii Novgorod, 603600, Russia

    A. E. Bol’shakova, N. B. Mel’nikova, L. N. Nistratova, T. V. Salikova, S. A. Gavrilova & E. V. Krasil’nikova

  2. SOZIDATEL Company, Moscow, 127299, Russia

    I. P. P’yanzina

Authors
  1. A. E. Bol’shakova
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  2. N. B. Mel’nikova
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  3. L. N. Nistratova
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  4. I. P. P’yanzina
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  5. T. V. Salikova
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  6. S. A. Gavrilova
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  7. E. V. Krasil’nikova
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Corresponding author

Correspondence to A. E. Bol’shakova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 7, pp. 45 – 51, July, 2012.

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Bol’shakova, A.E., Mel’nikova, N.B., Nistratova, L.N. et al. Suspension based on calcium carbonate and sodium hyaluronate for the prevention and treatment of bone diseases. Pharm Chem J 46, 449–455 (2012). https://doi.org/10.1007/s11094-012-0819-8

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  • DOI: https://doi.org/10.1007/s11094-012-0819-8

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