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Synthesis and pharmacological properties of alkylammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid

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A series of ammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid with some alkylamines have been obtained. It is established that these compounds possess hypotensive, antiarrhythmic, and anticoagulative activities depending on the structure of the alkylamine constituents.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 44, No. 9, pp.3–5, September, 2010.

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Shepel’, F.G., Zozulya, R.N., Shepel’, D.F. et al. Synthesis and pharmacological properties of alkylammonium salts of N,N′-malonyl-bis-p-aminobenzoic acid. Pharm Chem J 44, 469–471 (2010). https://doi.org/10.1007/s11094-010-0493-7

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  • DOI: https://doi.org/10.1007/s11094-010-0493-7

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