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Comparative Study of the Adsorption Activity of Medicinal Sorbents

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Pharmaceutical Chemistry Journal Aims and scope

A comparative study of the adsorption activity of some medical sorbents with respect to physiologically active substances with different molecular weights has been carrried out. It is shown that Siliks (Polysorb MP) exhibits greater ability to adsorb proteins in comparison to other sorbents. In contrast, the carbon-based sorbents do not absorb proteins but have a high affinity for low-and medium-molecular-weight substances. The adsorption activity of Smecta in acid media is close to that of carbons. Due to similar chemical properties, the Siliks and Enterosgel preparations demonstrate analogous adsorption characteristics.

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References

  1. A. A. Chuiko, ed., Medicinal Chemistry and Clinical Application of Silicon Dioxide [in Russian], Naukova Dumka, Kiev (2003).

    Google Scholar 

  2. N. A. Belyakov, ed., Enterosorption [in Russian], Tsentr Sorbtsionnykh Tekhnologii, Leningrad (1991).

    Google Scholar 

  3. Enterosgel, Enterosorptive Technologies in Medicine [in Russian], A collection of works from a scientific practical conference, Novosibirsk—Moscow (1999).

  4. Biosorption Methods and Preparations in Treatment and Therapy Practice. Collection of Works of the First Scientific-Practical Conference [in Ukrainian], Kiiv (1997).

  5. USSR State Pharmacopoeia [in Russian], 10th Ed., Meditsina, Moscow (1968), pp. 141, 161.

  6. V. V. Men(shikov, ed., Laboratory Methods for Clinical Research (Manual) [in Russian], Meditsina, Moscow (1987), pp. 216–217.

    Google Scholar 

  7. I. M. Korenman, Photometric Analysis. Methods for Determining Organic Compounds [in Russian], Khimiya, Moscow (1975).

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  8. USSR State Pharmacopoeia, No. 2, 11th Ed., Meditsina, Moscow (1989), pp. 30, 34.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 7, pp. 30–33, July, 2008.

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Markelov, D.A., Nitsak, O.V. & Gerashchenko, I.I. Comparative Study of the Adsorption Activity of Medicinal Sorbents. Pharm Chem J 42, 405–408 (2008). https://doi.org/10.1007/s11094-008-0138-2

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  • DOI: https://doi.org/10.1007/s11094-008-0138-2

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