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Imidazole Derivatives. XXX. Synthesis and Antitumor Activity of 4-amyloxy-3-nitroacetophenone 2-imidazolinyl-2-hydrazone and Related Compounds

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The antitumor properties of 2-imidazolinyl-2-hydrazones of acetophenones with various substituents in the benzene ring have been studied. High activity is found for 4-amyloxy-3-nitroacetophenone 2-imidazolinyl-2-hydrazone, which points to the expediency of its further investigation.

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Authors and Affiliations

  1. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan, Armenia

    M. A. Iradyan, R. A. Aroyan, G. M. Stepanyan, F. G. Arsenyan & B. T. Garibdzhanyan

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  1. M. A. Iradyan
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  2. R. A. Aroyan
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  3. G. M. Stepanyan
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  4. F. G. Arsenyan
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  5. B. T. Garibdzhanyan
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 7, pp. 10–11, July, 2008.

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Iradyan, M.A., Aroyan, R.A., Stepanyan, G.M. et al. Imidazole Derivatives. XXX. Synthesis and Antitumor Activity of 4-amyloxy-3-nitroacetophenone 2-imidazolinyl-2-hydrazone and Related Compounds. Pharm Chem J 42, 384–386 (2008). https://doi.org/10.1007/s11094-008-0133-7

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  • DOI: https://doi.org/10.1007/s11094-008-0133-7

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