Summary
Dural metastases are found at autopsy in 8–9% of patients with advanced systemic cancer. They arise either by direct extension from skull metastases or by hematogeneous spread. Dural metastases are often clinically asymptomatic but they may produce progressive neurological deficits and sometimes subdural hematomas. MRI may be misleading when the metastasis simulates a meningioma or when a subdural hematoma masks the underlying tumor. Whenever possible, surgical removal is the most appropriate treatment. The prognosis is poor because of the progressive systemic cancer but prolonged survival has been reported in operated patients, when the systemic cancer was controlled.
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References
JB Posner (1995) Intracranial metastases. In: Neurologic Complications of Cancer FA Davis Philadelphia 77–82
PC Meyer TG Reah (1953) ArticleTitleSecondary neoplasms of the central nervous system and meninges Br J Cancer 7 438–448 Occurrence Handle13126386
PC Ambiavagar J Sher (1978) ArticleTitleSubdural hematoma secondary to metastatic neoplasm: report of two cases and a review of the literature Cancer 42 2015–2018 Occurrence Handle361219
BK Kleinschmidt-DeMasters (2001) ArticleTitleDural metastases. A retrospective surgical and autopsy series Arch Pathol Lab Med 125 880–887 Occurrence Handle11419971
T Vasudev Rao DH Deshpande (1980) ArticleTitleMalignant subdural effusion A case report. Acta Neurochir (Wien) 52 61–65 Occurrence Handle10.1007/BF01400948
MW Pak HK Mak PK Ku CA Hasselt Particlevan (1996) ArticleTitleDural metastasis at medulla oblongata: a rare cause of vocal fold paralysis J Laryngol Otol 110 884–886 Occurrence Handle8949305
T Haisa T Kondo N Shinoura T Hara M Nasu (1996) ArticleTitleMalignant schwannoma metastasizing to the dura mater-case report Neurol Med Chir (Tokyo) 36 462–465
H Maezawa (1998) ArticleTitleDural metastasis in prostatic carcinoma on the middle fossa No To Shinkei 50 1034–1035 Occurrence Handle9866131
S Chirathivat MJ Post (1980) ArticleTitleCT demonstration of dural metastases in neuroblastoma J Comput Assist Tomogr 4 316–319 Occurrence Handle7372864
AM Bentley JC Keen (2003) ArticleTitleDural metastases in prostate cancer Clin Oncol (R Coll Radiol) 15 165–166
N Sato H Tsurushima A Matsumura K Meguro M Doi (1991) ArticleTitleA case of epidural hematoma due to dural metastasis No Shinkei Geka 19 447–450 Occurrence Handle1852252
K Murayama T Shimura K Isayama M Matsumoto K Ohwaki S Nakazawa (1983) ArticleTitleA case of skull and dural metastases of carcinoid tumor of the urinary bladder No Shinkei Geka 11 643–649 Occurrence Handle6621788
MW Penley YC Kim HF Pribram (1981) ArticleTitleSubdural metastases from prostatic adenocarcinoma Surg Neurol 16 131–134 Occurrence Handle10.1016/0090-3019(81)90114-2 Occurrence Handle7280985
A Kaur MR Harrigan PE MeKeever DA Ross (1999) ArticleTitleAdenoid cystic carcinoma metastatic to the dura: report of two cases J Neuro-oncol 44 267–273 Occurrence Handle10.1023/A:1006352307507
Y River A Schwartz JM Gomori D Soffer T Siegal (1996) ArticleTitleClinical significance of diffuse dural enhancement detected by magnetic resonance imaging J Neurosurg 85 777–783 Occurrence Handle8893714
T Oyoshi M Nakayama H Hirano S Shimokawa J Kuratsu (2000) ArticleTitleIntracranial dural metastasis of mediastinal seminoma-case report Neurol Med Chir (Tokyo) 40 423–426 Occurrence Handle10.2176/nmc.40.423
M Higuchi Y Fujimoto E Miyahara H Ikeda (1997) ArticleTitleIsolated dural metastasis from colon cancer Clin Neurol Neurosurg 99 135–137 Occurrence Handle10.1016/S0303-8467(96)00599-9 Occurrence Handle9213059
D Deleu F Geeter ParticleDe T Buisseret A Goossens J Caemaert G Ebinger (1989) ArticleTitleDural metastasis from laryngeal malignant carcinoid Am J Med 87 250–251
JR Perry JM Bilbao (1994) ArticleTitleMetastatic alveolar soft part sarcoma presenting as a dural-based cerebral mass Neurosurgery 34 168–170 Occurrence Handle8121554
D Vonofakos A Zieger H Marcu (1980) ArticleTitleSubdural hematoma associated with dural metastatic tumor Neuroradiology 20 213–218 Occurrence Handle10.1007/BF00336686 Occurrence Handle7465041
AM Scarrow PR Rajendran D Marion (2000) ArticleTitleMetastatic prostate adenocarcinoma of the dura mater Br J Neurosurg 14 473–474 Occurrence Handle10.1080/02688690050175328 Occurrence Handle11198774
JM Tomlin CH Alleyne (2002) ArticleTitleTransdural metastasis from adenocarcinoma of the prostate mimicking subdural hematoma: case report Surg Neurol 58 329–331 Occurrence Handle10.1016/S0090-3019(02)00835-2 Occurrence Handle12504300
CR McKenzie SS Rengachary DH McGregor AY Dixon DL Suskind (1990) ArticleTitleSubdural hematoma associated with metastatic neoplasm Neurosurgery 27 619–624 Occurrence Handle10.1097/00006123-199010000-00019 Occurrence Handle2172860
E Rouah JC Goodman RL Harper (1986) ArticleTitleAcute subdural hematoma and metastatic seminoma Neurology 36 418–420 Occurrence Handle3951713
D N'dri Oka G Varlet N Boni E Broalet L Boukassa V. Ba Zeze (2000) ArticleTitleDural metastasis of prostatic adenocarcinoma presenting as acute intracranial subdural hematoma: a case report J Neuroradiol 27 282–284 Occurrence Handle11223621
V Varlet D N'Dri Oka M Kakou A Echimane V Ba Zeze (2001) ArticleTitleSecondary subdural hematoma in dural metastasis of prostatic adenocarcinoma Rev Neurol (Paris) 157 1543–1545
SH Tseng CC Liao SM Lin Y Chen CT Shun (2003) ArticleTitleDural metastasis in patients with malignant neoplasm and chronic subdural hematoma Acta Neurol Scand 108 43–46 Occurrence Handle10.1034/j.1600-0404.2003.00080.x Occurrence Handle12807392
T Nagaya T Doi N Katsumata H Ishigure M Matsuda M Ito (1986) ArticleTitleSubdural hematoma associated with dural carcinomatosis of gastric cancer and DIC Gan No Rinsho 32 923–926 Occurrence Handle3747151
K Tasaki T Shima S Matsumura Y Okada M Nishida T Yamada S Okita R Kagawa (1990) ArticleTitleA case of subdural effusion secondary to dural metastasis of prostatic cancer: case report No Shinkei Geka 18 539–542 Occurrence Handle2395513
T Kinjo J Mukawa E Takara K Horikawa (1989) ArticleTitleChronic subdural hematoma following advanced cancer: report of three cases No Shinkei Geka 17 763–768 Occurrence Handle2586717
A Otsuka K Asakura K Takahashi T Tasaki K Okada Y Suzuki (1985) ArticleTitleNontraumatic chronic subdural hematoma due to dural metastases of breast cancer Case report. No Shinkei Geka 13 999–1004
Y Hirashima K Kamiyama S Endo A Takaku (1983) ArticleTitleSubdural hematoma due to metastatic dural carcinomatosis associated with DIC- a case report No Shinkei Geka 11 651–656 Occurrence Handle6621789
K Kamiya T Inagawa R Nagasako (1987) ArticleTitleChronic subdural hematoma due to dural metastasis: demonstration of adenocarcinoma cell nests in the fluid Case report. Neurol Med Chir (Tokyo) 27 892–898
A Sugawara S Miura Y Suda T Ohmi T Tanaka H Tateoka (1986) ArticleTitleChronic subdural hematoma secondary to metastasis of adenocarcinoma of the dura mater and skull-a case report Gan No Rinsho 32 190–195 Occurrence Handle3959340
S Mashiyama O Fukawa S Mitani S Ito K Ito S Asano T Sai (2000) ArticleTitleChronic subdural hematoma associated with malignancy: report of three cases No Shinkei Geka 28 173–178 Occurrence Handle10666738
M Endo M Hamano K Watanabe S Wakai (1999) ArticleTitleCombined chronic subdural and acute epidural hematoma secondary to metastatic hepatocellular cancer: case report No Shinkei Geka 27 331–334 Occurrence Handle10347847
T Kuroki M Matsumoto T Kushida T Ohtsuka M Uchino H Nishikawa (1994) ArticleTitleNontraumatic subdural hematoma secondary to dural metastasis of lung cancer: case report and review of the literature No Shinkei Geka 22 857–862 Occurrence Handle8090269
V D'Angelo L. Bizzozero RA Fontana N Colombo E Minola (1988) ArticleTitleChronic subdural hematoma associated with dural metastasis from mammary carcinoma Case report and review of the literature. Acta Neurol (Napoli) 10 206–212
I Nagayama H Katoh M Sakumoto M Itoh K Yoshida (1993) ArticleTitleSubdural hematoma associated with dural metastasis from parasinusal sinus cancer: a case report and review of the literature ORL J Otorhinolaryngol Relat Spec 55 240–243 Occurrence Handle8336926
M Sato T Saito K Yamaguchi H Sakuma (1994) ArticleTitleA case of acute subdural hematoma due to dural metastasis from malignant pleural mesothelioma No Shinkei Geka 22 247–251 Occurrence Handle8133966
B Krempien (1970) ArticleTitleDurahygroma in carcinosis of the dura mater Zentralbl Allg Pathol 113 409–414 Occurrence Handle5273468
M Khalfallah PH Roche D Figarrela-Branger S Malca W Pellet (1999) ArticleTitleDural metastases mimicking meningioma Report of a case. Neurochirurgie 45 250–254
OM Shaffi P Wrightson (1975) ArticleTitleDural invasion by pituitary tumours N Z Med J 81 386–390 Occurrence Handle1057087
IA Auer RN Auer (1998) ArticleTitleMetastatic dermatofibrosarcoma protuberans mimicking meningioma Clin Neuropathol 17 190–193 Occurrence Handle9707332
MD Johnson SZ Powell PJ Boyer RJ Weil PL Moots (2002) ArticleTitleDural lesions mimicking meningiomas Hum Pathol 33 1211–1226 Occurrence Handle10.1053/hupa.2002.129200 Occurrence Handle12514791
P Tagle P Villanueva G Torrealba I Huete (2002) ArticleTitleIntracranial metastasis or meningioma. An uncommon clinical diagnostic dilemma Surg Neurol 58 241–245 Occurrence Handle10.1016/S0090-3019(02)00831-5 Occurrence Handle12480230
SM Lippman AC Buzaid RP Iacono DV Steinbronn TH Stanisic MA Rennels PJ Yang HS Garewal FR Ahmann (1986) ArticleTitleCranial metastases from prostate cancer simulating meningioma: report of two cases and review of the literature Neurosurgery 19 820–823 Occurrence Handle3785633
JY Ahn NK Kim D Oh HJ Ahn (2002) ArticleTitleThymic carcinoma with brain metastasis mimicking meningioma J Neurooncol 58 193–199 Occurrence Handle10.1023/A:1016225915434 Occurrence Handle12187955
JE Castaldo JL Bernat FA Meier AR Schned (1983) ArticleTitleIntracranial metastases due to prostate carcinoma Cancer 52 1739–1747 Occurrence Handle6616423
S Sgouros AR Walsh (1994) ArticleTitleSynchronous dural and cutaneous metastases along the distribution of the external carotid artery Br J Neurosurg 8 617–619 Occurrence Handle7857546
F Caputi E Lamaida R Gazzeri (1999) ArticleTitleAcute subdural hematoma and pachymeningitis carcinomatosa: case report Rev Neurol (Paris) 155 383–385
DM Turner CJ Graf (1982) ArticleTitleNontraumatic subdural hematoma secondary to dural metastasis: case report and review of the literature Neurosurgery 11 678–680 Occurrence Handle7155333
CL Cheng J Greenberg LA Hoover (1988) ArticleTitleProstatic adenocarcinoma metastatic to chronic subdural hematoma membranes Case report. J Neurosurg 68 642–644
M Bergmann Z Puskas K Kuchelmeister (1992) ArticleTitleSubdural hematoma due to dural metastasis: case report and review of the literature Clin Neurol Neurosurg 94 235–240 Occurrence Handle10.1016/0303-8467(92)90095-K Occurrence Handle1327614
RW Leech FT Welch GA Ojemann (1974) ArticleTitleSubdural hematoma secondary to metastatic dural carcinomatosis Case report. J Neurosurg 41 610–613
MN Bucci SM Farhat (1986) ArticleTitleMetastatic adenocarcinoma of the prostate as a cause of subdural hematoma J Urol 135 803–804 Occurrence Handle3959210
DS Russell H Cairns (1934) ArticleTitleSubdural false membrane or haematoma (pachymeningitis interna haemorrhagica) in carcinomatosis and sarcomatosis of the dura mater Brain 57 32–48
CS Rumana KR Hess WM Shi R Sawaya (1998) ArticleTitleMetastatic brain tumors with dural extension J Neurosurg 89 552–558 Occurrence Handle9761048
RE Steg AR Frank DM Lefkowitz (1993) ArticleTitleComplex partial status epilepticus in a patient with dural metastases Neurology 43 2389–2392 Occurrence Handle8232965
JJ Raizer LM Angelis ParticleDe (2000) ArticleTitleCerebral sinus thrombosis diagnosed by MRI and MR venography in cancer patients Neurology 54 1222–1226 Occurrence Handle10746588
L Nadel IF Braun JP Muizelaar FJ Laine (1991) ArticleTitleTumoral thrombosis of cerebral venous sinuses: preoperative diagnosis using magnetic resonance phase imaging Surg Neurol 35 189–195 Occurrence Handle10.1016/0090-3019(91)90070-P Occurrence Handle1996447
RL II Tyrrell CV Bundschuh MT Modic (1987) ArticleTitleDural carcinomatosis: MR demonstration J Comput Assist Tomogr 11 329–332 Occurrence Handle3819135
DD Weaver DL Cross HR Winn JA Jane (1984) ArticleTitleComputed tomographic findings in metastatic dural carcinomatosis Surg Neurol 21 190–194 Occurrence Handle10.1016/0090-3019(84)90341-0 Occurrence Handle6701757
M Bendszus M Warmuth-Metz R Burger R Klein JC Tonn L. Solymosi (2001) ArticleTitleDiagnosing dural metastases: the value of 1H magnetic resonance spectroscopy Neuroradiology 43 285–289 Occurrence Handle10.1007/s002340000419 Occurrence Handle11338410
DJ Quint JE McGillicuddy (1994) ArticleTitleMeningeal metastasis of the cerebellopontine angle demonstrating « dural tail » sign Can Assoc Radiol J 45 40–43 Occurrence Handle8118713
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Laigle-Donadey, F., Taillibert, S., Mokhtari, K. et al. Dural metastases. J Neurooncol 75, 57–61 (2005). https://doi.org/10.1007/s11060-004-8098-1
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DOI: https://doi.org/10.1007/s11060-004-8098-1