The aim of the present work was to study the distribution of cell contact protein β-catenin in the choroid plexus and ependyma of the lateral ventricles of the brain. Experiments were performed using frontal sections of brains from Wistar rats (n = 10) using polyclonal antibodies to β-catenin. Preparations were analyzed under the microscope in transmitted light and by confocal laser microscopy. The distribution of β-catenin in different projections was studied by three-dimensional reconstruction. The results identified differences in the distributions of this protein in the ependyma and choroid plexus. In contrast to the ependyma, β-catenin is distributed in choroid plexus cells in the same way as in monolayer epithelial tissues (at the basal and lateral margins of the cells). This may be evidence that the ependyma and epithelium of the choroid plexus are of different tissue types, despite their common origin.
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Translated from Morfologiya, Vol. 149, No. 1, pp. 33–37, Januray–February, 2016.
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Kirik, O.V., Sufieva, D.A., Nazarenkova, A.V. et al. Cell Contact Protein β-Catenin in Ependymal and Epithelial Cells in the Choroid Plexus of the Lateral Ventricles of the Brain. Neurosci Behav Physi 47, 117–121 (2017). https://doi.org/10.1007/s11055-016-0373-z
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DOI: https://doi.org/10.1007/s11055-016-0373-z