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Analysis of Locomotor Activity in Decerebrate Cats Using Electromagnetic and Epidural Electrical Stimulation of the Spinal Cord

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Epidural and electromagnetic stimulation of the cervical and lumbar parts of the spinal cord at a frequency of 5 Hz was found to induce locomotor activity in decerebrate cats on a moving treadmill belt. Differences were found in the initiation of locomotion using different means and locations of stimulation. Stimulation at a frequency of 0.3 Hz induced single reflex responses in the muscles of the fore- and hindlimbs. Analysis of the structure of reflex responses showed that locomotor ability depends on the level of involvement and activity of polysynaptic reflex pathways. The hypothesis that that stepping generators are activated indirectly via activation of the dorsal roots during epidural stimulation and by more direct activation of the neural locomotor network during electromagnetic stimulation of the spinal cord is discussed.

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Authors and Affiliations

  1. I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034, St. Petersburg, Russia

    I. N. Bogacheva, P. E. Musienko, N. A. Shcherbakova, T. R. Moshonkina, A. A. Savokhin & Yu. P. Gerasimenko

Authors
  1. I. N. Bogacheva
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  2. P. E. Musienko
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  3. N. A. Shcherbakova
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  4. T. R. Moshonkina
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  5. A. A. Savokhin
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  6. Yu. P. Gerasimenko
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Correspondence to I. N. Bogacheva.

Additional information

Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 98, No. 9, pp. 1079–1093, September, 2012.

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Bogacheva, I.N., Musienko, P.E., Shcherbakova, N.A. et al. Analysis of Locomotor Activity in Decerebrate Cats Using Electromagnetic and Epidural Electrical Stimulation of the Spinal Cord. Neurosci Behav Physi 44, 552–559 (2014). https://doi.org/10.1007/s11055-014-9950-1

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  • DOI: https://doi.org/10.1007/s11055-014-9950-1

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