Cerebral hemodynamics were studied in northern schoolchildren aged 7–17 years living in the absolute (Magadan Region, 62°N, n = 167) and relative (Arkhangelsk Region, 61°N, n = 52) discomfort zones by transcranial Doppler sonography and rheoencephalography. New data were obtained on measures of blood flow in the main cerebral arteries, vessel tone, vasomotor reactivity, and the development of these values in children in two northern regions of the Russian Federation. Blood flow rates in the cerebral arteries of Evens and Koryaks, who form the aboriginal population, were significantly greater than in children of incoming settlers. There was a tendency to an increase in the tone of resistance vessels in northern children, which was more marked among children living in the harsher conditions of the Magadan Region. Parameters characterizing individual adaptive rearrangements of cerebral circulation and the features possibly associated with the formation of the “polar metabolic type” are discussed.
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References
A. P. Avtsyn and A. G. Marachev, “Adaptation and maladaptation in inhabitants of the Far North,” Fiziol. Cheloveka, 34, No. 4, 3–14 (1975).
N. A. Agadzhanyan, “Adaptation and the body’s reserves,” in: Physical Culture and Sport [in Russian], Moscow (1983).
N. A. Agadzhanyan, V. K. Stepanov, D. G. Strelkov, and O. M. Ruseikina, “Assessment of the human body’s functional reserves using an ultrasound Dopplerographic method,” Fiziol. Cheloveka, 34, No. 3, 65–69 (2008).
E. R. Boiko, Physiological-Biochemical Bases of Human Activity in the North [in Russian], Urals Branch, Russian Academy of Sciences, Ekaterinburg (2005).
B. V. Gaidar, V. E. Parfenov, and D. V. Svistov, Practical Guidelines for Transcranial Dopplerography [in Russian], VMA, St. Petersburg (1995).
T. V. Godovykh and V. V. Godovykh, Healthy Children in Chukotka, [in Russian], North-East Scientific Center, Far Eastern Branch, Russian Academy of Sciences, Magadan (2006).
O. S. Golovin, Geography of the Magadan Region [in Russian], Kordis, Magadan (2003).
P. D. Gorizontov, Homeostasis [in Russian], Meditsina, Moscow (1981).
G. M. Danishevskii, Human Pathology and the Prophylaxis of Diseases in the North [in Russian], Meditsina, Moscow (1968).
L. K. Dobrodeeva and L. V. Sen’kova, “Status of the immune system in humans in the North,” in: Problems in Human Ecology [in Russian], Northern Medical Institute, Arkhangelsk (2000), pp. 69–76.
V. G. Evdokimov, O. V. Rogachevskaya, and N. G. Varlamova, Modulating Effects of the Factors of the North on the Cardiorespiratory System During Ontogeny in Humans [in Russian], Urals Branch, Russian Academy of Sciences, Ekaterinburg (2007).
L. B. Ivanov and V. A. Makarov, Lectures in Clinical Rheography [in Russian], MBN, Moscow (2000).
M. N. Koroleva, “Use of extracranial USD in studies of cerebral hemodynamics in children,” in: Experience at K. A. Raukhfus Pediatric City Hospital No. 19: Collection of Scientific Reports [in Russian], St. Petersburg (1999), pp. 71–77.
S. G. Krivoshchekov, V. P. Leutin, and M. G. Chukhrova, Psychophysiological Aspects of Incomplete Adaptation [in Russian], Novosibirsk (1998).
V. G. Lelyuk and S. E. Lelyuk, Ultrasound Angiology [in Russian], Realnoe Vremya, Moscow (2003).
G. P. Luzin, E. E. Lazarev, L. N. Shirokova, and R. V. Yakovlev, Regional Data for the North of Russia [in Russian], Kola Scientific Center, USSR Academy of Sciences, Apatity (1993).
A. L. Maksimov and V. Sh. Belkin, A. L. Maksimov and V. Sh. Belkin, “Biomedical and climatoecological aspects of regionalization of territories with extreme environmental conditions,” Vestnik DVO RAN, 3, 28–39 (2005).
A. L. Maksimov, E. V. Pegova, and T. P. Bartosh, “Experience in the complex assessment of health and psychophysiological status in adolescents in the Magadan Region,” in: Humans in the North: Systems Mechanisms of Adaptation: Collection of Reports [in Russian], North-East Scientific Center, Far Eastern Branch, Russian Academy of Sciences, Magadan (2007), pp. 111–137.
V. I. Medvedev, Human Adaptation [in Russian], Institute of the Human Brain, Russian Academy of Sciences, St. Petersburg (2003).
Yu. E. Moskalenko, A. I. Beketov, and R. S. Orlov, Cerebral Circulation. Physicochemical Study Approaches [in Russian], Nauka, Leningrad (1988).
P. A. Motavkin and V. M. Chertok, Histophysiology of the Vascular Mechanisms of Cerebral Circulation [in Russian], Meditsina, Moscow (1980).
A. D. Nozdrachev and R. P. Bukolova, “Sympathetic ganglia as peripheral neuroendocrine centers,” Usp. Fiziol. Nauk., 24, No. 1, 80–98 (1993).
A. D. Nozdrachev, L. I. Kolosova, A. B. Moiseeva, and O. V. Ryabchikova, “The role of the peripheral nervous system in the relationship between the immune system and the brain,” Ros. Fiziol. Zh. im. I. M. Sechenova, 86, No. 6, 728–742 (2000).
A. D. Nozdrachev and M. P. Chernyshova, Visceral Reflexes [in Russian], Leningrad University Press, Leningrad (1989).
L. E. Panin, Energy Aspects of Adaptation [in Russian], Meditsina, Leningrad (1978).
A. Yu. Ratner, Late Complications of Birth Damage to the Nervous System [in Russian], Kazan (1990).
M. A. Ronkin and L. B. Ivanov, Rheography in Clinical Practice [in Russian], MBC, Moscow (1999).
Yu. A. Rosin, Dopplerography of Brain Blood Vessels in Children [in Russian], St. Petersburg Knizhnoe Press, St. Petersburg (2004).
M. P. Roshchevskii,V. G. Evdokimov, N. G. Varlamova, and A. S. Orlov, “Regional and seasonal characteristics of the functioning of the cardiorespiratory system in inhabitants of the North,” Fiziol. Cheloveka, 20, No. 6, 75–81 (1994).
V. M. Salazkina, L. K. Bragina, and I. Ya. Kalinovskaya, Dyscirculation in the Vertebrobasilar System in Pathology of the Cervical Segment of the Spine [in Russian], Meditsina, Moscow (1977).
A. D. Slonim, Physiological Mechanisms of Natural Adaptation of Animals and Humans [in Russian], Nauka, Moscow (1964).
Yu. G. Solonin, “Seasonal changes in physiological functions in inhabitants of the North,” Fiziol. Cheloveka, 21, No. 6, 70–75 (1995).
S. I. Soroko, E. A. Burykh, S. S. Bekshaev, et al., “Characteristics of the formation of systems activity in the brain in children in the conditions of the European North,” Ros. Fiziol. Zh. im. I. M. Sechenova, 92, No. 8, 905–929 (2006).
S. I. Soroko,V. P. Rozhkov, and E. A. Burykh, “Parameters of cerebral circulation in children of 7–11 years living in the European North,” Fiziol. Cheloveka, 34, No. 6, 37–50 (2008).
A. V. Tkachev, E. R. Boiko, Z. D. Gubkina, et al., “The endocrine system and metabolism in humans in the North,” Komi Scientific Center, Urals Branch, Russian Academy of Sciences, Syktyvkar (1992).
V. A. Khil’ko, Yu. E. Moskalenko, B. V. Gaidar, and V. E. Parfenov, “Cerebral vessel reactivity based on transcranial Dopplerography data,” Fiziol. Cheloveka, 75, No. 11, 1486–1500 (1989).
A. R. Shakhnovich and V. A. Shakhnovich, Diagnosis of Cerebral Circulatory Lesions. Transcranial Dopplerography [in Russian], Meditsina, Moscow (1996).
Kh. Kh. Yarullin, Clinical Rheoencephalography [in Russian], Meditsina, Moscow (1983).
L. A. Yasyukova, Minimal Cerebral Dysfunction in Children [in Russian], Meditsina, Moscow (1997).
R. Aaslid, “Transcranial Doppler examination techniques,” in: Transcranial Doppler Sonography, Springer Verlag,Vienna, New York (1986), pp. 39–59.
S. L. Bakker, F. E. de Leeuw, T. den Heiher, et al., “Cerebral haemodynamics in the elderly: the Rotterdam study,” Neuroepidemiology, 23, 178–188 (2004).
H. Bode, Pediatric Applications of Transcranial Doppler Sonography, Springer Verlag, Vienna, New York (1988).
H. Bode and U. Wais, “Age dependence of flow velocities in basal cerebral arteries,” Arch. Dis. Child., 63, 606–611 (1988).
I. T. Jarjour, C. M. Ryan, and D. J. Becker, “Regional cerebral blood flow during hypoglycaemia in children with IDDM,” Diabetologia, 38, No. 9, 1090–1095 (1995).
J. D. Pickard, R. J. Nelson, and A. H. Lovick, “Cerebrovascular reactivity and its application,” in: Cerebral Blood Flow and Metabolism, Manchester University Press, Manchester, New York (1990), pp. 48–70.
Yu. Udomphorn, W. M. Armstead, and M. S. Vavilala, “Cerebral blood flow and autoregulation after pediatric traumatic brain injury,” Pediatr. Neurol., 38, No. 4, 225–234 (2008).
J. M. Valduera, M. Schultz, L. Harms, and K. M. Einhaupl, “Venous transcranial Doppler monitoring in acute dural sinus thrombosis,” Stroke, 26, 1196–1199 (1996).
M. S. Vavilala, M. Sean Kincaid, S. L. Muangman, et al., “Gender differences in cerebral blood flow velocity and autoregulation between the anterior and posterior circulations in healthy children,” Pediatr. Res., 58, No. 3, 574–582 (2005).
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Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 97, No. 10, pp. 1113–1133, October, 2011.
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Rozhkov, V.P., Nikolaev, I.V. & Soroko, S.I. Comparative Assessment of Cerebral Hemodynamics in School-Age Children Living in the Far Eastern and European North. Neurosci Behav Physi 43, 629–642 (2013). https://doi.org/10.1007/s11055-013-9784-2
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DOI: https://doi.org/10.1007/s11055-013-9784-2