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Distribution of genes and recombination on wheat homoeologous group 6 chromosomes: a synthesis of available information

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Abstract

Presence of genes in gene-rich regions on wheat chromosomes has been widely reported. However, there is a lack of information on the precise characterization of these regions with respect to the distribution of genes and recombination. We attempted to critically analyze the available data to characterize gene-rich regions and to study the distribution of genes and recombination on wheat homoeologous group 6 chromosomes which are a reservoir of several useful genes controlling traits of economic importance. Consensus physical and genetic linkage maps were constructed for homoeologous group 6 using physical and genetic mapping data. Five major gene-rich regions were identified on homoeologous group 6 chromosomes, with two on the short and three on long arm. More than 90% of marker or gene loci were present in these five gene-rich regions, which comprise about 30% of the total physical chromosomal length. The gene-rich regions were mainly present in the distal 60% regions of the chromosomes. About 61% of the total loci map in the most distal regions which span only about 4% of the physical length of the chromosome. A range of sub-microscopic regions within each gene-rich region were also identified. Comparisons of the consensus physical and genetic linkage maps revealed that recombination occurred mainly in the gene-rich regions. Seventy percent of the total recombination occurred in the two most distally located regions that span only 4% of the physical length of the chromosomes. The relationship of recombination to the gene-rich region is not linear with distance from the centromere, especially on the long arm. The kb/cM estimates for group 6 chromosomes ranged from 146 kb in the gene-rich to about 10 Mb in the gene-poor region. The information obtained here is vital in understanding wheat genome structure and organization, which may lead in developing better strategies for positional cloning in wheat and related cereals.

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References

  • M.D. Bennet J.B. Smith (1976) ArticleTitleNuclear DNA amounts in angiosperms Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci. 274 227–274

    Google Scholar 

  • J.L. Bennetzen P. SanMiguel M. Chen A. Tikhonov M. Francki et al. (1998) ArticleTitleGrass genomes Proc. Natl. Acad. Sci. USA 95 1975–1978

    Google Scholar 

  • J. Brown V. Sundaresan (1991) ArticleTitleA recombination hotspot in the maize A1 intragenic region Theor. Appl. Genet. 81 185–188

    Google Scholar 

  • B. Burr R.A. Burr K.H. Thompson M.C. Albertsen C.W. Stuber (1988) ArticleTitleGene mapping with recombinant inberds in maize Genetics 118 519–526 Occurrence Handle1:CAS:528:DyaL1cXhs1amtL4%3D Occurrence Handle3366363

    CAS  PubMed  Google Scholar 

  • R. Buschges K. Hollricher R. Panstruga G. Simmon M. Wolter et al. (1997) ArticleTitleThe barley Mlo gene: a novel control element of plant pathogen resistance Cell 88 695–705 Occurrence Handle10.1016/S0092-8674(00)81912-1 Occurrence Handle9054509

    Article  PubMed  Google Scholar 

  • C.A. Curtis A.J. Lukaszewski (1991) ArticleTitleGenetic linkage between C-bands and storage protein genes of tetraploid wheat Theor. Appl. Genet. 81 245–252

    Google Scholar 

  • J. Dvorak K.Y. Chen (1984) ArticleTitleDistribution of nonstructural variation between wheat cultivars along chromosome 6Bp: evidence from the linkage map and physical map of the arm Genetics 106 325–333

    Google Scholar 

  • C. Du G.E. Hart (1998) ArticleTitle Triticum turgidum L. 6A and 6B recombinant substitution lines: extended linkage maps and characterization of residual background alien genetic variation Theor. Appl. Genet. 96 645–653

    Google Scholar 

  • J.D. Faris K.M. Haen B.S. Gill (2000) ArticleTitleSaturation mapping of a gene-rich recombination hot spot region in wheat Genetics 154 823–835

    Google Scholar 

  • J.D. Faris J.P. Fellers S.A. Brooks B.S. Gill (2003) ArticleTitleA bacterial artificial chromosome contig spanning the major domestication locus Q in wheat and identification of a candidate gene Genetics 164 311–321 Occurrence Handle1:CAS:528:DC%2BD3sXkvFOiur0%3D Occurrence Handle12750342

    CAS  PubMed  Google Scholar 

  • C. Feuillet B. Keller (1999) ArticleTitleHigh gene density is conserved at syntenic loci of small and large grass genomes Proc. Natl. Acad. Sci. USA 96 8265–8270

    Google Scholar 

  • M.W. Ganal N.D. Young S.D. Tanksley (1989) ArticleTitlePulsed field gel electrophoresis and physical mapping of large DNA fragments in the Tm-2a region of chromosome 9 in tomato Mol. Gen. Genet. 215 395–400

    Google Scholar 

  • B.S. Gill B. Friebe T.R. Endo (1991a) ArticleTitleStandard karyotypenomenclature system for the description of chromosome bands, and structural aberrations in wheat (Triticum aestivum) Genome 34 830–839

    Google Scholar 

  • K.S. Gill E.L. Lubbers B.S. Gill W.J. Roupp T.S. Cox (1991b) ArticleTitleA genetic linkage map of Triticum tauschii (DD) and its relationship to the D genome of bread wheat (AABBDD) Genome 34 362–374

    Google Scholar 

  • K.S. Gill B.S. Gill T.R. Endo (1993) ArticleTitleA chromosome region-specific mapping strategy reveals gene-rich telomeric ends in wheat Chromosoma 102 374–381 Occurrence Handle10.1007/BF00360401 Occurrence Handle1:CAS:528:DyaK2cXht1Kltbs%3D

    Article  CAS  Google Scholar 

  • K.S. Gill B.S. Gill (1994) ArticleTitleMapping in the realm of polyploidy: the wheat model BioEssay 16 841–846

    Google Scholar 

  • K.S. Gill B.S. Gill T.R. Endo E.V. Boyko (1996a) ArticleTitleIdentification and high density mapping of gene-rich regions of group 5 chromosomes of wheat Genetics 143 1001–1012

    Google Scholar 

  • K.S. Gill B.S. Gill T.R. Endo T. Taylor (1996b) ArticleTitleIdentification and high-density mapping of gene-rich regions in chromosome group 1 of wheat Genetics 144 1883–1891

    Google Scholar 

  • L. Givardi Y. Xia K.J. Edwards P.S. Schnable B.J. Nikolau (1994) ArticleTitleThe relationship between genetic and physical distances in the cloned al-sh2 interval of the Zea mays L. genome Proc. Natl. Acad. Sci. USA 91 8268–8272

    Google Scholar 

  • A. Graner A. Jahoor J. Schondelmaier H. Siedler K. Pillen G. Fischbeck G. Wenzel R.G. Hermann (1991) ArticleTitleConstruction of an RFLP map of barley Theor. Appl. Genet. 83 250–256

    Google Scholar 

  • G.E. Hart (1997) Homoeologous group 6 P.E. McGuire C.O. Qualset (Eds) Progress in Genome Mapping of Wheat and Related Species: Joint Proceedings of 5th and 6th Public Workshops of ITMI, September 1–3, 1995, NorwichUK; August 30–31, 1996, Sydney, AustraliaGenetic Resources Conservation Program UC Davis CA, USA 89–105

    Google Scholar 

  • J. Jia K.M. Devos S. Chao T.E. Miller S.M. Reader M.D. Gale (1996) ArticleTitleRFLP-based maps of the homoeologous group 6 chromosomes of wheat and their application on the tagging of pm-12, a powdery mildew resistance gene transferred from Aegilops speltoides to wheat Theor. Appl. Genet. 92 559–565

    Google Scholar 

  • R.S. Kota K.S. Gill B.S. Gill (1993) ArticleTitleA cytogenetically based physical map of chromosome 1B in common wheat Genome 36 548–554 Occurrence Handle1:CAS:528:DyaK3sXmtFyqs7w%3D

    CAS  Google Scholar 

  • G. Kunzel L. Korzum A. Meister (2000) ArticleTitleCytologically integrated physical restriction fragment length polymorphism maps for the barley genome based on translocation breakpoints Genetics 154 397–412 Occurrence Handle10628998

    PubMed  Google Scholar 

  • T. Lahaye K. Shirasu P. Schulze-Lefert (1998) ArticleTitleChromosome landing at the barley Rar1 locus Mol. Gen. Genet. 260 92–101

    Google Scholar 

  • M.-C. Luo Z.L. Yang J. Dvorak (1998) ArticleTitlePosition effects of ribosomal RNA multigene loci on meiotic recombination in wheat Genetics 149 1105–1113

    Google Scholar 

  • C.L. Marino J.C. Nelson Y.H. Lu M.E. Sorrells P. Leroy N.A. Tuleen C.R. Lopes G.E. Hart (1996) ArticleTitleMolecular genetic maps of the group 6 chromosomes of hexaploid wheat (Triticum aestivum L. em. Thell) Genome 39 359–366 Occurrence Handle1:CAS:528:DyaK28XjtVyjur4%3D

    CAS  Google Scholar 

  • R.A. McIntosh G.E. Hart K.M. Devos M.D. Gale W.J. Rogers (1998) Catalogue of gene symbols for wheat A.E. Slinkard (Eds) Proc. 9th Int. Wheat Genet. Symp. University Extension Press, University of Saskatchewan ManitobaCanada

    Google Scholar 

  • McIntosh R.A., Devos K.M., Duncovsky J. and Worland W.J. 2000. Catalogue of gene symbols for wheat: 2000 and 2001 Supplement: http://wheat.pw.usda.gov/ggpages/wgc/2001upd.html.

  • J. Puechberty A.M. Laurent S. Gimenez A. Billault M.E.B. Laurent et al. (1999) ArticleTitleGenetic and physical analyses of the centromeric and pericentromeric regions of human chromosome 5: recombination across 5cen Genomics 56 274–287

    Google Scholar 

  • D. Sandhu J.A. Champoux S.N. Bondareva K.S. Gill (2001) ArticleTitleIdentification and physical localization of useful genes and markers to a major gene-rich region on wheat group 1S chromosomes Genetics 157 1735–1747

    Google Scholar 

  • R. Schmidt J. West K. Love Z. Lenehan C. Lister et al. (1995) ArticleTitlePhysical map and organization of Arabidopsis thaliana chromosome 4 Science 270 480–484 Occurrence Handle1:CAS:528:DyaK2MXovVersb4%3D Occurrence Handle7570002

    CAS  PubMed  Google Scholar 

  • P.S. Schnable A.P. Hsia B.J. Nikolau (1998) ArticleTitleGenetic recombination in plants Curr. Opin. Plant Biol. 1 123–129

    Google Scholar 

  • Sears E.R. 1954. The aneuploids of common wheat. Research Bulletin 572. University of Missouri Agric. Exp. Stn., pp. 1–58.

  • G. Segal M. Sarfatti M.A. Schaffer N. Ori D. Zamir et al. (1992) ArticleTitleCorrelation of genetic and physical structure in the region surrounding the I2 Fusarium oxysporum resistance locus in tomato Mol. Gen. Genet. 231 179–185

    Google Scholar 

  • M.M. Shah K.S. Gill (2001) ArticleTitleHigh Density mapping of gene-rich region present on homoeologous group 5L of wheat and barley Barley Genet. Newslett. 31 18

    Google Scholar 

  • G. Tranquilli D. Lijavetzky G. Muzzi J. Dubcovsky (1999) ArticleTitleGenetic and physical characterization of grain texture-related loci in diploid wheat Mol. Gen. Genet. 262 846–850

    Google Scholar 

  • J. Werner T.R. Endo B.S. Gill (1992) ArticleTitleToward a cytogenetically based physical map of the wheat genome Proc. Natl. Acad. Sci. USA 89 11307–11311

    Google Scholar 

  • Y. Weng N.A. Tuleen G.E. Hart (2000) ArticleTitleExtended physical maps and a consensus physical map of the homoeologous group-6 chromosomes of wheat (Triticum aestivum L. em Thell.) Theor. Appl. Genet. 100 519–527

    Google Scholar 

  • H.B. Zhang G.B. Martin S.D. Tanksley R.A. Wing (1994) ArticleTitleMap-based cloning in crop plants: tomato as a model system. II. Isolation and characterization of a set of overlapping yeast artificial chromosomes encompassing the jointless locus Mol. Gen. Genet. 244 613–621

    Google Scholar 

Download references

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Authors and Affiliations

  1. Institute of Biotechnology and Genetic Engineering (IBGE), NWFP Agricultural University, Peshawar, 25000, Pakistan

    Mohammad Maroof Shah

  2. Graduate School of Science and Technology, Niigata University, Igarashi 2-8050, 950-2181, Niigata, Japan

    Amjad Hassan

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  1. Mohammad Maroof Shah
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  2. Amjad Hassan
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Correspondence to Mohammad Maroof Shah.

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Shah, M., Hassan, A. Distribution of genes and recombination on wheat homoeologous group 6 chromosomes: a synthesis of available information. Mol Breeding 15, 45–53 (2005). https://doi.org/10.1007/s11032-004-1844-4

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