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Novel multicomponent reactions involving isoquinoline or phenanthridine and activated acetylenic ester in the presence of heterocyclic NH or 1,3-dicarbonyl compounds

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Abstract

Multicomponent reactions involving azines (phenanthridine or isoquinoline) and dimethyl acetylenedicarboxylate were undertaken in the presence of heterocyclic NH compounds (indole, 2-methyl indole, 3-methyl indole, carbazole and 3,6-dibromocarbazole) or 1,3-dicarbonyl compounds such as N,N′-dimethylbarbituric acid, 1,3-diethyl-2-thiobarbituric acid, acetylacetone, 1,3-diphenyl-1,3-propandione and cyclopentan-1,3-dione to generate enaminoesters in good yields.

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Authors and Affiliations

  1. Department of Chemistry, The University of Sistan and Balouchestan, P.O. Box 98135-674, Zahedan, Iran

    Mahmoud Nassiri, Malek Taher Maghsoodlou, Reza Heydari & Sayyed Mostafa Habibi Khorassani

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  1. Mahmoud Nassiri
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  2. Malek Taher Maghsoodlou
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  3. Reza Heydari
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  4. Sayyed Mostafa Habibi Khorassani
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Correspondence to Malek Taher Maghsoodlou.

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Nassiri, M., Maghsoodlou, M.T., Heydari, R. et al. Novel multicomponent reactions involving isoquinoline or phenanthridine and activated acetylenic ester in the presence of heterocyclic NH or 1,3-dicarbonyl compounds. Mol Divers 12, 111–117 (2008). https://doi.org/10.1007/s11030-008-9083-y

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