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A mainstream monitoring system for respiratory CO2 concentration and gasflow

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Abstract

Continuous respiratory gas monitoring is an important tool for clinical monitoring. In particular, measurement of respiratory \(\hbox {CO}_2\) concentration and gasflow can reflect the status of a patient by providing parameters such as volume of carbon dioxide, end-tidal \(\hbox {CO}_2,\) respiratory rate and alveolar deadspace. However, in the majority of previous work, \(\hbox {CO}_2\) concentration and gasflow have been studied separately. This study focuses on a mainstream system which simultaneously measures respiratory \(\hbox {CO}_2\) concentration and gasflow at the same location, allowing for volumetric capnography to be implemented. A non-dispersive infrared monitor is used to measure \(\hbox {CO}_2\) concentration and a differential pressure sensor is used to measure gasflow. In developing this new device, we designed a custom airway adapter which can be placed in line with the breathing circuit and accurately monitor relevant respiratory parameters. Because the airway adapter is used both for capnography and gasflow, our system reduces mechanical deadspace. The finite element method was used to design the airway adapter which can provide a strong differential pressure while reducing airway resistance. Statistical analysis using the coefficient of variation was performed to find the optimal driving voltage of the pressure transducer. Calibration between variations and flows was used to avoid pressure signal drift. We carried out targeted experiments using the proposed device and confirmed that the device can produce stable signals.

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Acknowledgments

This research is partially supported by the National Natural Science Foundation of China (No. 61471260), Natural Science Foundation of Tianjin (No. 12jcqnjc00500), Supported by Program for New Century Excellent Talents in University (NCET-12-0400).

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Authors and Affiliations

  1. School of Electronic Information Engineering, Tianjin University, Tianjin, People’s Republic of China

    Jiachen Yang, Bobo Chen, Haitao Wang & Jianxiong Zhou

  2. Tianjin Yaan Polytron Technologies Inc, Tianjin, People’s Republic of China

    Jiachen Yang

  3. Departments of Anesthesiology and Bioengineering, University of Utah, Salt Lake City, UT, USA

    Kyle Burk

Authors
  1. Jiachen Yang
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  2. Bobo Chen
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  3. Kyle Burk
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  4. Haitao Wang
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  5. Jianxiong Zhou
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Correspondence to Bobo Chen.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Yang, J., Chen, B., Burk, K. et al. A mainstream monitoring system for respiratory CO2 concentration and gasflow. J Clin Monit Comput 30, 467–473 (2016). https://doi.org/10.1007/s10877-015-9739-y

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  • DOI: https://doi.org/10.1007/s10877-015-9739-y

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