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The NMR structure of the TC10- and Cdc42-interacting domain of CIP4

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References

  • Aspenstrom P (1997) A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr Biol 7:479–487

    Article  Google Scholar 

  • Bryant NJ, Govers R, James DE (2002) Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3:267–277

    Article  Google Scholar 

  • Chang L, Adams RD, Saltiel AR (2002) The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes. Proc Natl Acad Sci USA 99:12835–12840

    Article  ADS  Google Scholar 

  • Chang L, Chiang SH, Saltiel AR (2004) Insulin signaling and the regulation of glucose transport. Mol Med 10:65–71

    Google Scholar 

  • Czech MP, Buxton JM (1993) Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes. J Biol Chem 268:9187–9190

    Google Scholar 

  • Delaglio F, Grzesiek S, Vuister G, Zhu W, Pfeifer J, Bax A (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6:277–293

    Article  Google Scholar 

  • Feltham JI, Dotsch V, Raza S, Manor D, Cerione RA, Suteliffe MJ, Wagner G, Oswald RE (1997) Definition of the switch surface in the solution structure of Cdc42Hs. Biochemistry 36:8755–8766

    Article  Google Scholar 

  • Herrmann T, Guntert P, Wuthrich K (2002) Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J Mol Biol 319:209–227

    Article  Google Scholar 

  • Holm L, Sander C (1995) Dali: a network tool for protein structure comparison. Trends Biochem Sci 20:478–480

    Article  Google Scholar 

  • Itoh T, Erdmann KS, Roux A, Habermann B, Werner H, De Camilli P (2005) Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev Cell 9:791–804

    Article  Google Scholar 

  • Jhun BH, Rampal AL, Liu H, Lachaal M, Jung CY (1992) Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling. J Biol Chem 267:17710–17715

    Google Scholar 

  • Kneller DG, Goddard TD (1997) SPARKY 3.105 edit. University of California, San Francisco

    Google Scholar 

  • Kobashigawa Y, Kumeta H, Ogura K, Inagaki F (2009) Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method. J Biomol NMR 43:145–150. doi:10.1007/s10858-008-9296-5

    Article  Google Scholar 

  • Lodhi IJ, Chiang SH, Chang L, Vollenweider D, Watson RT, Inoue M, Pessin JE, Saltiel AR (2007) Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes. Cell Metab 5:59–72

    Article  Google Scholar 

  • Maesaki R, Ihara K, Shimizu T, Kuroda S, Kaibuchi K, Hakoshima T (1999) The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Mol Cell 4:793–803

    Article  Google Scholar 

  • Modha R, Campbell LJ, Nietlispach D, Buhecha HR, Owen D, Mott HR (2008) The Rac1 polybasic region is required for interaction with its effector PRK1. J Biol Chem 283:1492–1500

    Article  Google Scholar 

  • Tian L, Nelson DL, Stewart DM (2000) Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules. J Biol Chem 275:7854–7861

    Article  Google Scholar 

  • Watson RT, Kanzaki M, Pessin JE (2004) Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr Rev 25:177–204

    Article  Google Scholar 

  • Yang J, Holman GD (1993) Comparison of GLUT4 and GLUT1 subcellular trafficking in basal and insulin-stimulated 3T3–L1 cells. J Biol Chem 268:4600–4603

    Google Scholar 

Download references

Acknowledgments

This work was supported (in part) by Targeted Proteins Research Program (TPRP) from Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.

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Correspondence to Fuyuhiko Inagaki.

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Kobashigawa, Y., Kumeta, H., Kanoh, D. et al. The NMR structure of the TC10- and Cdc42-interacting domain of CIP4. J Biomol NMR 44, 113–118 (2009). https://doi.org/10.1007/s10858-009-9317-z

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  • DOI: https://doi.org/10.1007/s10858-009-9317-z

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