Abstract
Numerous modification methods have been reported to enhance the corrosion resistance of magnesium with positive results. However, little attention has been paid on their impact on micro-environment, particularly the ion concentration and local pH value. In this study, two different coatings were prepared on magnesium, one with porous micro-arc oxidation (MAO) coating alone, and the other with additional polymer polyhydroxybutyrate (PHB) membrane using spinning technique. Their in vitro corrosional and biological behaviors were investigated and compared. Both coatings were found to reduce the degradation rate of magnesium, but an additionally deposited PHB membrane was superior to MAO-coated magnesium since it could produce a micro-environment with preferable local pH value and ion concentration for osteoblast proliferation. Our study suggests that micro-environment should be another critical issue in evaluation of a modification method for orthopaedic implants.
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Acknowledgments
The authors gratefully acknowledge the financial support of National Basic Research Program of China (Grant No. 2012CB619100), the National Natural Science Foundation of China (Grant Nos. 21105029, 51102097, 51072057) and Special funding for university talent introduction of Guangdong Province (GX N).
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Honglong Li and Haobo Pan have contributed equally to this work.
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Li, H., Pan, H., Ning, C. et al. Magnesium with micro-arc oxidation coating and polymeric membrane: an in vitro study on microenvironment. J Mater Sci: Mater Med 26, 147 (2015). https://doi.org/10.1007/s10856-015-5428-0
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DOI: https://doi.org/10.1007/s10856-015-5428-0