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Characterisation, corrosion resistance and in vitro bioactivity of manganese-doped hydroxyapatite films electrodeposited on titanium

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Abstract

This work elucidated the corrosion resistance and in vitro bioactivity of electroplated manganese-doped hydroxyapatite (MnHAp) film on NaOH-treated titanium (Ti). The NaOH treatment process was performed on Ti surface to enhance the adhesion of the MnHAp coating on Ti. Scanning electron microscopy images showed that the MnHAp coating had needle-like apatite crystals, and the approximately 10 μm thick layer was denser than HAp. Energy-dispersive X-ray spectroscopy analysis revealed that the MnHAp crystals were Ca-deficient and the Mn/P molar ratio was 0.048. X-ray diffraction confirmed the presence of single-phase MnHAp, which was aligned vertically to the substrate. Fourier transform infrared spectroscopy indicated the presence of phosphate bands ranging from 500 to 650 and 900 to 1,100 cm−1, and a hydroxyl band at 3,571 cm−1, which was characteristic of HAp. Bond strength test revealed that adhesion for the MnHAp coating was more enhanced than that of the HAp coating. Potentiodynamic polarisation test showed that the MnHAp-coated surface exhibited superior corrosion resistance over the HAp single-coated surface. Bioactivity test conducted by immersing the coatings in simulated body fluid showed that MnHAp coating can rapidly induce bone-like apatite nucleation and growth. Osteoblast cellular tests revealed that the MnHAp coating was better at improving the in vitro biocompatibility of Ti than the HAp coating.

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Acknowledgments

This work was supported by the National Basic Research Program of China (“973” Program, No. 2011CB503700), the outstanding doctoral academic projects of the University of Electronic Science and Technology of China (No. YBXSZC20131042) and the Natural Science Foundation of China (No. 61071026). The authors thank Xuexin Wang for his assistance in the revision of the manuscript.

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Authors and Affiliations

  1. Institute of Life Science and Technology, University of Electronic Science and Technology of China, No. 4 of Section 2, Jianshe North Road, Chengdu, 610054, Sichuan, China

    Yong Huang, Qiongqiong Ding, Shuguang Han, Yajing Yan & Xiaofeng Pang

  2. International Centre for Materials Physics, Chinese Academy of Science, Shenyang, 110015, China

    Xiaofeng Pang

  3. College of Lab Medicine, Hebei North University, Zhangjiakou, 075000, China

    Yong Huang

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  1. Yong Huang
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Correspondence to Xiaofeng Pang.

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Huang, Y., Ding, Q., Han, S. et al. Characterisation, corrosion resistance and in vitro bioactivity of manganese-doped hydroxyapatite films electrodeposited on titanium. J Mater Sci: Mater Med 24, 1853–1864 (2013). https://doi.org/10.1007/s10856-013-4955-9

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