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Anticorrosion and cytocompatibility behavior of MAO/PLLA modified magnesium alloy WE42

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Abstract

Recently, biodegradable magnesium alloys have been introduced in the field of cardiovascular stents to avoid the specific drawbacks of permanent metallic implants. However, the major obstacle of the clinical use of magnesium-based materials is their rapid corrosion rate. In this paper, a composite micro-arc oxidation/poly-l-lactic acid (MAO/PLLA) coating was fabricated on the surface of the magnesium alloy WE42 to improve its corrosion resistance and the cytocompatibility of the modified materials was also investigated for safety aim. In our study, the morphology of materials was analyzed by Scanning electron microscopy. Potentiodynamic polarization was used to evaluate the corrosion behavior of the samples and corrosion weight loss was used to demonstrate their degradation rate. Furthermore, we applied cytotoxicity test in testing the cytocompatibility of the modified samples. The results showed that the PLLA coating effectively sealed the microcracks and micropores on the surface of the MAO coating by physical interlocking to interfere the corrosion ions. The corrosion rate was decreased and the cyototoxicity test showed that the MAO/PLLA composite coating WE42 had good cytocompatibility.

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Acknowledgment

The authors gratefully acknowledge the financial support of Natural Science Foundation of Tianjin in China (08JC2DJC17900).

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Authors and Affiliations

  1. Department of Cardiology, Tianjin Chest Hospital, Tianjin, 300051, People’s Republic of China

    Lu Cao & Yin Liu

  2. School of Materials Science and Engineering, Tianjin University, Tianjin, 300072, People’s Republic of China

    Meiqing Guo, Ping Lu & Xinhua Xu

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  1. Meiqing Guo
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  2. Lu Cao
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  3. Ping Lu
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  4. Yin Liu
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  5. Xinhua Xu
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Corresponding author

Correspondence to Xinhua Xu.

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Lu Cao and Ping Lu contributed equally to this work.

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Guo, M., Cao, L., Lu, P. et al. Anticorrosion and cytocompatibility behavior of MAO/PLLA modified magnesium alloy WE42. J Mater Sci: Mater Med 22, 1735–1740 (2011). https://doi.org/10.1007/s10856-011-4354-z

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  • DOI: https://doi.org/10.1007/s10856-011-4354-z

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