Abstract
Dopamine (DA), a biological neurotransmitter which has a similar structure to the essential adhesive component of mussel protein, was here used to modify polyaniline (PANI) via a one-step chemical oxidization method. The as-fabricated DA-PANI resulted from different DA to aniline (An) mole ratio showed different morphology. Compared to pure PANI, the modified PANI exhibited greatly enhanced adhesion force to the substrate. In addition, the biocompatibility and dispersibility of DA-modified PANI were also significantly improved compared with pure PANI. More importantly, the incorporation of poor conductive PDA did not enormously weaken the electrical conductivity of PANI, and it still showed good electrical conductivity as the DA/An mole ratio was not higher than 0.48.
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References
Huang S, Liang N, Hu Y, Zhou X, Abidi N (2016) Polydopamine-assisted surface modification for bone biosubstitutes. Biomed Res Int 2016:2389895
Ye Q, Zhou F, Liu W (2011) Bioinspired catecholic chemistry for surface modification. Chem Soc Rev 40:4244–4258
Fan X, Lin L, Dalsin JL, Messersmith PB (2005) Biomimetic anchor for surface-initiated polymerization from metal substrates. J Am Chem Soc 127:15843–15847
Lee H, Dellatore SM, Miller WM, Messersmith PB (2007) Mussel-inspired surface chemistry for multifunctional coatings. Science 318:426–430
Liu Y, Ai K, Lu L (2014) Polydopamine and its derivative materials: synthesis and promising applications in energy, environmental, and biomedical fields. Chem Rev 114:5057–5115
Son EJ, Kim JH, Kim K, Park CB (2016) Quinone and its derivatives for energy harvesting and storage materials. J Mater Chem A 4:11179–11202
Liu Y, Ai K, Liu J, Deng M, He Y, Lu L (2013) Dopamine-melanin colloidal nanospheres: an efficient near-infrared photothermal therapeutic agent for in vivo cancer therapy. Adv Mater 25:1353–1359
Tian J, Deng SY, Li DL, Shan D, He W, Zhang XJ, Shi Y (2013) Bioinspired polydopamine as the scaffold for the active AuNPs anchoring and the chemical simultaneously reduced graphene oxide: characterization and the enhanced biosensing application. Biosens Bioelectron 49:466–471
Kim JH, Lee M, Park CB (2014) Inside cover: polydopamine as a biomimetic electron gate for artificial photosynthesis (Angew. Chem. Int. Ed. 25/2014). Angewandte Chemie 53:6364–6368
Gao H, Sun Y, Zhou J, Xu R, Duan H (2013) Mussel-inspired synthesis of polydopamine-functionalized graphene hydrogel as reusable adsorbents for water purification. ACS Appl Mater Interf 5:425–433
Zhang W, Yang FK, Pan ZH, Zhang J, Zhao BX (2014) Bio-inspired dopamine functionalization of polypyrrole for improved adhesion and conductivity. Macromol Rapid Commun 35:350–354
Zhang W, Pan Z, Yang FK, Zhao B (2015) A facile in situ approach to polypyrrole functionalization through bioinspired catechols. Adv Func Mater 25:1588–1597
Kim S, Jang LK, Park HS, Lee JY (2016) Electrochemical deposition of conductive and adhesive polypyrrole-dopamine films. Scientific Rep 6:30475
Wang Z, Zhou L, Yu P, Liu Y, Chen J, Liao J, Li W, Chen W, Zhou W, Yi X, Ouyang K, Zhou Z, Tan G, Ning C (2016) Polydopamine-assisted electrochemical fabrication of polypyrrole nanofibers on bone implants to improve bioactivity. Macromol Mater Eng 301:1288–1294
Li C, Bai H, Shi G (2009) Conducting polymer nanomaterials: electrosynthesis and applications. Chem Soc Rev 38:2397–2409
Oh W-K, Kwon OS, Jang J (2013) Conducting polymer nanomaterials for biomedical applications: cellular interfacing and biosensing. Polym Rev 53:407–442
Tran HD, Li D, Kaner RB (2009) One-dimensional conducting polymer nanostructures: bulk synthesis and applications. Adv Mater 21:1487–1499
Llorens E, Armelin E, del Mar Pérez-Madrigal M, del Valle L, Alemán C, Puiggalí J (2013) Nanomembranes and nanofibers from biodegradable conducting polymers. Polymers 5:1115–1157
Borriello A, Guarino V, Schiavo L, Alvarezperez MA, Ambrosio L (2011) Optimizing PANi doped electroactive substrates as patches for the regeneration of cardiac muscle. J Mater Sci Mater Med 22:1053–1062
Zhang QS, Yan YH, Li SP, Feng T (2009) Synthesis of a novel biodegradable and electroactive polyphosphazene for biomedical application. Biomed Mater 4:035008
Huang L, Zhuang X, Hu J (2008) Synthesis of biodegradable and electroactive multiblock polylactide and aniline pentamer copolymer for tissue engineering applications. Biomacromolecules 9:850–858
Qazi TH, Rai R, Boccaccini AR (2014) Tissue engineering of electrically responsive tissues using polyaniline based polymers: a review. Biomaterials 35:9068–9086
Yu QZ, Shi MM, Deng M, Wang M, Chen HZ (2008) Morphology and conductivity of polyaniline sub-micron fibers prepared by electrospinning. Mater Sci Eng, B 150:70–76
Li F, Yang L, Zhao C, Du Z (2011) Electroactive gold nanoparticles/polyaniline/polydopamine hybrid composite in neutral solution as high-performance sensing platform. Anal Methods 3:1601–1607
Mihai I, Addiégo F, Del Frari D, Bour J, Ball V (2013) Associating oriented polyaniline and eumelanin in a reactive layer-by-layer manner: composites with high electrical conductivity. Colloids Surf, A 434:118–125
Moon IJ, Kim MW, Choi HJ, Kim N, You C-Y (2016) Fabrication of dopamine grafted polyaniline/carbonyl iron core-shell typed microspheres and their magnetorheology. Colloids Surf, A 500:137–145
Wang H-B, Zhang H-D, Jiang Y-L, Li X-L, Liu Y-M (2015) Determination of adenine and guanine by a dopamine-melanin nanosphere-polyaniline nanocomposite modified glassy carbon electrode. Anal Lett 49:226–235
Wang X, Lee PS (2015) A polydopamine coated polyaniline single wall carbon nanotube composite material as a stable supercapacitor cathode in an organic electrolyte. J Mater Res 30:3575–3583
Xie C, Li P, Han L, Wang Z, Zhou T, Deng W, Wang K, Lu X (2017) Electroresponsive and cell-affinitive polydopamine/polypyrrole composite microcapsules with a dual-function of on-demand drug delivery and cell stimulation for electrical therapy. NPG Asia Mater 9:e358
Boomi P, Prabu HG, Mathiyarasu J (2013) Synthesis and characterization of polyaniline/Ag-Pt nanocomposite for improved antibacterial activity. Colloids Surf B Biointerfaces 103:9–14
Boomi P, Prabu HG, Mathiyarasu J (2014) Synthesis, characterization and antibacterial activity of polyaniline/Pt-Pd nanocomposite. Eur J Med Chem 72:18–25
Eisa WH, Zayed MF, Abdel-Moneam YK, Zeid AMA (2014) Water-soluble gold/polyaniline core/shell nanocomposite: synthesis and characterization. Synth Met 195:23–28
Shabana S, Sonawane SH, Ranganathan V, Pujjalwar PH, Pinjari DV, Bhanvase BA, Gogate PR, Ashokkumar M (2017) Improved synthesis of aluminium nanoparticles using ultrasound assisted approach and subsequent dispersion studies in di-octyl adipate. Ultrason Sonochem 36:59–69
Wang J, Zhang K, Zhao L (2014) Sono-assisted synthesis of nanostructured polyaniline for adsorption of aqueous Cr(VI): effect of protonic acids. Chem Eng J 239:123–131
DE Medeiros DSDSDWO, Dantas TNC, Perira MR, Giacometi JA, Fonseca JLC (2003) Zeta potential and doping in polyaniline dispersions. Mater Sci 21:251–258
Jastrzebska MM, Isotalo H, Paloheimo J, Stubb H (1996) Electrical conductivity of synthetic DOPA-melanin polymer for different hydration states and temperatures. J Biomater Sci Polym Ed 7:577–586
Balint R, Cassidy NJ, Cartmell SH (2014) Conductive polymers: towards a smart biomaterial for tissue engineering. Acta Biomater 10:2341–2353
Bidez PR, Li S, MacDiarmid AG, Venancio EC, Wei Y, Lelkes PI (2006) Polyaniline, an electroactive polymer, supports adhesion and proliferation of cardiac myoblasts. J Biomater Sci Polym Ed 17:199–212
Gilmore KJ, Kita M, Han Y, Gelmi A, Higgins MJ, Moulton SE, Clark GM, Kapsa R, Wallace GG (2009) Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components. Biomaterials 30:5292–5304
Guo Y, Li M, Mylonakis A, Han J, Macdiarmid AG, Chen X, Lelkes PI, Wei Y (2007) Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications. Biomacromolecules 8:3025–3034
Humpolicek P, Kasparkova V, Saha P, Stejskal J (2012) Biocompatibility of polyaniline. Synth Met 162:722–727
Zhang W, Zhou YK, Feng K, Trinidad J, Yu AP, Zhao BX (2015) Morphologically controlled bioinspired dopamine-polypyrrole nanostructures with tunable electrical properties. Adv Electron Mater 1:205–214
Acknowledgements
This work was supported by the National Nature Science Foundation of China (31271009, 81271689), the Fundamental Research Funds for the Central Universities (No. 2011121001), the Program for New Century Excellent Talents in University, and the Program for New Century Excellent Talents in Fujian Province University and the Xiamen Municipal Science and Technology project (3502Z20144026).
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Tan, J., Xie, Z., Zhang, Z. et al. Dopamine modified polyaniline with improved adhesion, dispersibility, and biocompatibility. J Mater Sci 53, 447–455 (2018). https://doi.org/10.1007/s10853-017-1520-9
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DOI: https://doi.org/10.1007/s10853-017-1520-9