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Hydrogen peroxide versus water synthesis of bioglass–nanocrystalline hydroxyapatite composites

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Abstract

This article reports a comparison of the structural and textural properties of bioglass–hydroxyapatite (HA) composites obtained in the SiO2–CaO–P2O5 system by sol–gel method, with different amounts of hydrogen peroxide (3% H2O2) or water (H2O). X-ray diffraction, Raman, and FT-IR spectroscopy reveal the presence of nanocrystalline HA. Scanning electron microscopy images illustrate that the HA phase is mainly distributed on the glass surface. The results point out that the sintering at 550 °C of a sol–gel derived SiO2–CaO–P2O5 bioglass leads to a single crystalline phase of HA, and validate a new processing method for obtaining bioglass–HA composites. Structural analyses of the investigated composites indicate the existence of a silicate network built up from Q3 and Q2 units. The replacement of water with hydrogen peroxide has as consequence the increase of depolymerization degree of silica network. Textural properties were investigated with N2-adsorption technique. The composites prepared with hydrogen peroxide exhibit a more uniform and narrow mesoporous distribution that recommends them for drug uptake and release applications. It was found that the specific surface area and pore volume are clearly influenced by the H2O2(H2O):TEOS molar ratio.

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Acknowledgements

This research was accomplished in the framework of PNII PCCE-101/2008 project granted by the Romanian National University Research Council—CNCSIS.

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Authors and Affiliations

  1. Institute for Interdisciplinary Research in Bio-Nano-Sciences, Faculty of Physics, Babes-Bolyai University, M. Kogalniceanu 1, 400084, Cluj-Napoca, Romania

    G. Melinte, L. Baia, V. Simon & S. Simon

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  1. G. Melinte
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  2. L. Baia
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  3. V. Simon
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  4. S. Simon
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Correspondence to L. Baia.

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Melinte, G., Baia, L., Simon, V. et al. Hydrogen peroxide versus water synthesis of bioglass–nanocrystalline hydroxyapatite composites. J Mater Sci 46, 7393–7400 (2011). https://doi.org/10.1007/s10853-011-5700-8

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