Abstract
Conduct disorder (CD) is associated with a number of adverse psychosocial outcomes in adulthood. There is consistent evidence that CD is predictive of antisocial behavior, but mixed evidence that CD is predictive of other externalizing and internalizing disorders. Further, externalizing and internalizing disorders are often associated with similar psychosocial outcomes as CD. However, relatively little work has examined whether forms of psychopathology (e.g., externalizing and/or internalizing disorders) mediates the relationship between youth CD and adult psychosocial outcomes. The present study examined associations between youth CD and adult psychosocial outcomes and sought to identify forms of psychopathology that may potentially mediate this relationship. Participants completed self-report measures of psychosocial functioning and semi-structured diagnostic interviews during adolescence and young adulthood. Analyses found that most domains of adult psychosocial functioning were associated with youth CD. Adult antisocial behavior was the only form of psychopathology predicted by CD. Adult antisocial behavior appeared to mediate the relationship between CD and marital status, life satisfaction, and being in jail and partially mediated the relationship between CD and family support and global functioning. These data suggest that reducing the progression to adult antisocial behavior may improve multiple psychosocial outcomes among those with a history of CD.
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American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington: American Psychiatric Association.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed., rev.). Washington: American Psychiatric Association.
Andrews, F. M., & Withey, S. B. (1976). Social indicators of well-being: Americans’ perceptions of life quality. New York: Plenum Press.
Angold, A., Costello, E. J., & Erkanli, A. (1999). Comorbidity. Journal of Child Psychology and Psychiatry and Allied Disciplines, 40, 57–87.
Bardone, A., Moffitt, T., Caspi, A., Dickson, N., Stanton, W., & Silva, P. (1998). Adult physical health outcomes of adolescent girls with conduct disorder, depression, and anxiety. Journal of the American Academy of Child & Adolescent Psychiatry, 37, 594–601.
Baron, R. M., & Kenny, D. A. (1986). The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173–1182.
Biederman, J., Petty, C. R., Dolan, C., Hughes, S., Mick, E., Monuteaux, M. C., et al. (2008). The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up study. Psychological Medicine, 38, 1027–1036.
Burke, J., Loeber, R., Lahey, B., & Rathouz, P. (2005). Developmental transitions among affective and behavioral disorders in adolescent boys. Journal of Child Psychology and Psychiatry, 46, 1200–1210.
Campbell, A., Converse, P. E., & Rodgers, W. L. (1976). The quality of American life: Perceptions, evaluations, and satisfactions. New York: Russell Sage Foundation.
Cantwell, D., Lewinsohn, P., Rohde, P., & Seeley, J. (1997). Correspondence between adolescent report and parent report of psychiatric diagnostic data. Journal of Amer Academy of Child & Adolescent Psychiatry, 36, 610–619.
Chen, R., & Simons-Morton, B. (2009). Concurrent changes in conduct problems and depressive symptoms in early adolescents: a developmental person-centered approach. Development and Psychopathology, 21, 285–307.
Costello, E. J., Mustillo, S., Erkanli, A., Keeler, G., & Angold, A. (2003). Prevalence and development of psychiatric disorders in childhood and adolescence. Archives of General Psychiatry, 60, 837–844.
Ezpeleta, L., Domenech, J. M., & Angold, A. (2006). A comparison of pure and comorbid CD/ODD and depression. Journal of Child Psychology and Psychiatry, 47, 704–712.
Fergusson, D., & Horwood, L. (1998). Early conduct problems and later life opportunities. Journal of Child Psychology and Psychiatry and Allied Disciplines, 39, 1097–1108.
Fergusson, D., Horwood, J., & Ridder, E. (2005). Show me the child at seven: the consequences of conduct problems in childhood for psychosocial functioning in adulthood. Journal of Child Psychology and Psychiatry, 46, 837–849.
First, M. B., Gibbon, M., Spitzer, R. L., & Williams, J. B. W. (1996). Structured Clinical Interview for DSMIV Axis I disorders: Non-patient edition (SCID-I, Version 2.0). New York: Biometrics Research, New York State Psychiatric Institute.
Fritz, M. S., & MacKinnon, D. P. (2007). Required sample size to detect the mediated effect. Psychological Science, 18, 233–239.
Goldstein, R. B., Grant, B. F., Ruan, W. J., Smith, S. M., & Saha, T. D. (2006). Antisocial Personality Disorder with childhood-vs adolescence-onset conduct disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. The Journal of Nervous and Mental Disease, 194, 667.
Goodwin, R. D., & Hamilton, S. P. (2003). Lifetime comorbidity of antisocial personality disorder and anxiety disorders among adults in the community. Psychiatry Research, 117, 159–166.
Harley, M., Murtagh, A., & Cannon, M. (2008). Conduct disorder: psychiatry’s greatest opportunity for prevention. Psychological Medicine, 38, 929–931.
Harrington, R., Fudge, H., Rutter, M., Pickles, A., & Hill, J. (1991). Adult outcomes of childhood and adolescent depression: II. Links with antisocial disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 30, 434–439.
Hettema, J., Prescott, C., & Kendler, K. (2003). The effects of anxiety, substance use and conduct disorders on risk of major depressive disorder. Psychological Medicine, 33, 1423–1432.
Hill, J. (2003). Early identification of individuals at risk for antisocial personality disorder. The British Journal of Psychiatry, 182, s11–s14.
Keller, M. B., Lavori, P. W., Friedman, B., Nielsen, E., Endicott, J., McDonald-Scott, P., et al. (1987). The longitudinal interval follow-up evaluation. A comprehensive method for assessing outcome in prospective longitudinal studies. Archives of General Psychiatry, 44, 540–548.
Keyes, M. A., Iacono, W. G., & McGue, M. (2007). Early onset problem behavior, young adult psychopathology, and contextual risk. Twin Research and Human Genetics, 10, 45–53.
Kim-Cohen, J., Caspi, A., Moffitt, T. E., Harrington, H. L., Milne, B. S., & Poulton, R. (2003). Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective-longitudinal cohort. Archives of General Psychiatry, 60, 709–717.
King, S. M., Iacono, W. G., & McGue, M. (2004). Childhood externalizing and internalizing psychopathology in the prediction of early substance use. Addiction, 99, 1548–1559.
Laub, J. H., & Vaillant, G. E. (2000). Delinquency and mortality: a 50-year follow-up study of 1, 000 delinquent and non-delinquent boys. American Journal of Psychiatry, 157, 96–102.
Lewinsohn, P. M., Hops, H., Roberts, R. E., Seeley, J. R., & Andrews, J. A. (1993). Adolescent psychopathology.1. Prevalence and incidence of depression and other DSM-III-R disorders in high school students. Journal of Abnormal Psychology, 102, 133–144. 44, 540–548.
Lewinsohn, P. M., Rohde, P., Seeley, J. R., Klein, D. N., & Gotlib, I. H. (2003). Psychosocial functioning of young adults who have experienced and recovered from major depressive disorder during adolescence. Journal of Abnormal Psychology, 112, 353–363.
Loranger, A. W. (1988). Personality disorder examination (PDE) manual. Yonkers: DV Communications.
Loranger, A. W., Lenzenweger, M. F., Gartner, A. F., Susman, V. L., Herzig, J., Zammit, G. K., et al. (1991). Trait-state artifacts and the diagnosis of personality disorders. Archives of General Psychiatry, 48, 720–728.
Loranger, A. W., Sartorius, N., Andreoli, A., Berger, P., Buchheim, P., Channabasavanna, S. M., et al. (1994). The International Personality Disorder Examination: The World Health Organization/Alcohol, Drug Abuse, and Mental Health Administration international pilot study of personality disorders. Archives of General Psychiatry, 51, 215–224.
MacKinnon, D. P., Lockwood, C. M., Hoffman, J. M., West, S. G., & Sheeis, V. (2002). A comparison of methods to test mediation and other intervening variable effects. Psychological Methods, 7, 83–104.
Marcus, D. K., John, S. L., & Edens, J. F. (2004). A taxometric analysis of psychopathic personality. Journal of Abnormal Psychology, 113, 626–635.
Marcus, D. K., Lilienfeld, S. O., Edens, J. F., & Poythress, N. G. (2006). Is antisocial personality disorder continuous or categorical? A taxometric analysis. Psychological Medicine, 36, 1571–1581.
Marmorstein, N. R., & Iacono, W. G. (2003). Major depression and conduct disorder in a twin sample: gender, functioning, and risk for future psychopathology. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 225–233.
Masten, A. S., Burt, K., Roisman, G. I., Obradović, J., Long, J. D., & Tellegen, A. (2004). Resources and resilience in the transition to adulthood: continuity and change. Development and Psychopathology, 16, 1071–1094.
McGue, M., Iacono, W. G., & Krueger, R. (2006). The association of early adolescent problem behavior and adult psychopathology: a multivariate behavioral genetic perspective. Behavior Genetics, 36, 591–602.
Moffitt, T. E. (1993). Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychological Review, 100, 674–701.
Moffitt, T. E. (2006). A review of research on the taxonomy of life-course persistent versus adolescence-limited antisocial behavior. In F. T. Cullen, J. P. Wright, & K. R. Blevins (Eds.), Taking stock: The status of criminological theory (pp. 277–311). New Brunswick: Transaction Publishers.
Murrie, D., Marcus, D., Douglas, K., Lee, Z., Salekin, R., & Vincent, G. (2007). Youth with psychopathy features are not a discrete class: a taxometric analysis. Journal of Child Psychology and Psychiatry, 48, 714–723.
Muthén, L. K., & Muthén, B. O. (1998–2009). Mplus User’s Guide (5th ed.). Los Angeles: Muthén & Muthén.
Olino, T. M., Klein, D. N., Lewinsohn, P. M., Rohde, P., & Seeley, J. R. (2008). Longitudinal associations between depressive and anxiety disorders: a comparison of two trait models. Psychological Medicine, 38, 353–363.
Orvaschel, H., Puig-Antich, J., Chambers, W., Tabrizi, M. A., & Johnson, R. (1982). Retrospective assessment of prepubertal major depression with the Kiddie-SADS-E. Journal of the American Academy of Child and Adolescent Psychiatry, 21, 392–397.
Pardini, D., White, H. R., & Stouthamer-Loeber, M. (2007). Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood. Drug and Alcohol Dependence, 88, S38–S49.
Procidano, M. E., & Heller, K. (1983). Measures of perceived social support from friends and from family: three validation studies. American Journal of Community Psychology, 11, 1–24.
Rahdert, E. R. (1991). The adolescent assessment/referral system manual (DHHS Publication no. ADM91–1735). Rockville: National Institute on Drug Abuse.
Ramrakha, S., Bell, M., Paul, C., Dickson, N., Moffitt, T., & Caspi, A. (2007). Childhood behavior problems linked to sexual risk taking in young adulthood: a birth cohort study. Journal of the American Academy of Child & Adolescent Psychiatry, 46, 1272–1279.
Robins, L. N., & Price, R. K. (1991). Adult disorders predicted by childhood conduct problems: results from the NIMH Epidemiologic Catchment Area project. Psychiatry: Journal for the Study of Interpersonal Processes, 54, 116–132.
Rohde, P., Lewinsohn, P. M., Tilson, M., & Seeley, J. R. (1990). Dimensionality of coping and its relation to depression. Journal of Personality and Social Psychology, 58, 499–511.
Rohde, P., Lewinsohn, P. M., & Seeley, J. R. (1997). Comparability of telephone and face- to-face interviews in assessing axis I and II disorders. American Journal of Psychiatry, 154, 1593–1598.
Rohde, P., Lewinsohn, P. M., Seeley, J. R., Klein, D. N., Andrews, J. A., & Small, J. W. (2007). Psychosocial functioning of adults who experienced substance use disorders as adolescents. Psychology of Addictive Behaviors, 21, 155–164.
Roisman, G. I., Masten, A. S., Coatsworth, D., & Tellegen, A. (2004). Salient and emerging developmental tasks in the transition to adulthood. Child Development, 75, 123–133.
Rutter, M. (1994). Family discord and conduct disorder: cause, consequence, or correlate?: Contexts of interparental conflict and child behavior. Journal of Family Psychology, 8, 170–186.
Rutter, M., Kim-Cohen, J., & Maughan, B. (2006). Continuities and discontinuities in psychopathology between childhood and adult life. Journal of Child Psychology and Psychiatry, 47, 276–295.
Simonoff, E., Elander, J., Holmshaw, J., Pickles, A., Murray, R., & Rutter, M. (2004). Predictors of antisocial personality: continuities from childhood to adult life. The British Journal of Psychiatry, 184, 118–127.
Skilling, T. A., Quinsey, V. L., & Craig, W. M. (2001). Evidence of a taxon underlying serious antisocial behavior in boys. Criminal Justice and Behavior, 28, 450–470.
Sobin, C., Weissman, M. M., Goldstein, R. B., Adams, P., Wickramaratne, P., Warner, V., et al. (1993). Diagnostic interviewing for family studies: comparing telephone and face-to-face methods for the diagnosis of lifetime psychiatric disorders. Psychiatric Genetics, 3, 227–233.
Steinberg, L. (2008). A social neuroscience perspective on adolescent risk-taking. Developmental Review, 28, 78–106.
Webster-Stratton, C. (1996). Early-onset conduct problems: does gender make a difference? Journal of Consulting and Clinical Psychology, 64, 540–551.
Whisman, M. A., Tolejko, N., & Chatav, Y. (2007). Social consequences of personality disorders: probability and timing of marriage and probability of marital disruption. Journal of Personality Disorders, 21, 690–695.
Zoccolillo, M., Pickles, A., Quinton, D., & Rutter, M. (1992). The outcome of childhood conduct disorder: implications for defining adult personality disorder and conduct disorder. Psychological Medicine, 22, 971–986.
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This work was supported by National Institute of Mental Health research awards MH40501, MH50522, and DA12951 to Peter M Lewinsohn. The first author was supported by T32 MH018951 (PI: David A. Brent, M.D.).
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Olino, T.M., Seeley, J.R. & Lewinsohn, P.M. Conduct Disorder and Psychosocial Outcomes at Age 30: Early Adult Psychopathology as a Potential Mediator. J Abnorm Child Psychol 38, 1139–1149 (2010). https://doi.org/10.1007/s10802-010-9427-9
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DOI: https://doi.org/10.1007/s10802-010-9427-9