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Evaluation of ocular surface and meibomian glands in patients with uveitis related to oligoarticular juvenile idiopathic arthritis

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Abstract

Purpose

To evaluate ocular surface changes and meibomian gland scores in patients with oligoarticular juvenile idiopathic arthritis.

Materials and methods

This prospective study was conducted at Ege University School of Medicine, Department of Ophthalmology. A total of 34 eyes of 17 patients with oligoarticular juvenile idiopathic arthritis and 30 right eyes of 30 age and gender-matched healthy subjects were included. Besides ophthalmic examination Schirmer 1 test, tear film break up time, Oxford staining scale and meibography were performed.

Results

There was no statistically significant differences between groups in terms of age, mean intraocular pressure, mean Schirmer 1 test value, tear film break up time and Oxford staining score. The median upper and lower eyelid meiboscore were 1 ± 0.60 (IQR = 1), and 0 ± 0.34 (IQR = 0) in Group 1, and they were 1 ± 0.56 (IQR = 0), 1 ± 0.12 (IQR = 1) in Group 2. Also, mean upper and lower meiboscores were statistically similar (p values 0.068 and 0.545, respectively). However, the median total meiboscore was 1 ± 0.42 (IQR = 1) in Group 1 and 1 ± 0.66 (IQR = 1) in Group 2. The difference was statistically significant (p = 0.041).

Conclusion

Aqueous-deficient dry eye is a well-known condition in patients with rheumatologic diseases. However, evaporative dry eye and meibomian glands were not studied earlier. The current study demonstrated that total meiboscores of oligoarticular juvenile idiopathic arthritis patients are higher than normal subjects, which indicates a possible evaporative dry eye tendency in this entity.

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Funding

The study was conducted without any funding.

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Authors and Affiliations

  1. Department of Ophthalmology, School of Medicine, Ege University, Bornova, Turkey

    Cumali Degirmenci, Melis Palamar, Suzan Güven Yılmaz & Halil Ates

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  1. Cumali Degirmenci
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  2. Melis Palamar
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  3. Suzan Güven Yılmaz
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  4. Halil Ates
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Correspondence to Cumali Degirmenci.

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Degirmenci, C., Palamar, M., Güven Yılmaz, S. et al. Evaluation of ocular surface and meibomian glands in patients with uveitis related to oligoarticular juvenile idiopathic arthritis. Int Ophthalmol 40, 1863–1867 (2020). https://doi.org/10.1007/s10792-020-01357-w

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  • DOI: https://doi.org/10.1007/s10792-020-01357-w

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