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Inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements using two different methods

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Abstract

Purpose

To measure the inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements taken by the enhanced depth imaging of spectral-domain optical coherence tomography (EDI-OCT) in randomly selected subjects using two different protocols.

Methods

Twenty subjects of the Thessaloniki Eye Study database were randomly selected. The participants underwent EDI-OCT, and the choroidal thickness was measured on EDI images using two different protocols. All images were assessed by two examiners independently in two sessions in different days.

Results

The interobserver intraclass correlation coefficient (ICC) for average choroidal thickness was 0.944. The average ICC for central, Cmin, and Cmax choroidal thickness was 0.899, 0.863, and 0.955, respectively. The interobserver ICC for average choroidal volume was 0.932. Intraobserver repeatability ICC for grader 1 ranged between 0.925 and 0.9720 and for grader 2 between 0.913 and 0.994.

Conclusion

Choroidal thickness measurements by EDI-OCT showed a high inter- and intraobserver reproducibility.

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Acknowledgements

We would like to thank the ophthalmic technicians of the LaRCAO, 1st Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA Hospital, Irini Lachoura, Evgenia Zamba, Evmorfia Amiridou, Grigoria Tzoanou and Anastasia Rapti for their work and professionalism that greatly assisted the research. We are also grateful to Fei Yu from the Department of Biostatistics, UCLA, who provided advice that greatly assisted the research.

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Authors and Affiliations

  1. Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, 54621, Thessaloniki, Greece

    Angelakis Malamas, Nikolaos Dervenis, Vasileios Kilintzis, Angeliki Chranioti & Fotis Topouzis

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  1. Angelakis Malamas
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  2. Nikolaos Dervenis
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  3. Vasileios Kilintzis
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Correspondence to Fotis Topouzis.

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All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Declaration of Helsinki comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Malamas, A., Dervenis, N., Kilintzis, V. et al. Inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements using two different methods. Int Ophthalmol 39, 1061–1069 (2019). https://doi.org/10.1007/s10792-018-0909-z

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