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A sample predictive model for intraocular pressure following laser in situ keratomileusis for myopia and an “intraocular pressure constant”

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Abstract

Purpose

To describe a sample predictive model for intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) for myopia and an IOP constant.

Methods

The records of patients that underwent LASIK for myopia and myopic astigmatism via WaveLight Allegretto Wave Eye-Q 400 Hz excimer laser and Hansatome XP microkeratome were retrospectively reviewed. Patients with no systemic or ocular disease other than myopia or myopic astigmatism were included in the study. Preoperative and postoperative month 1 data and intraoperative data were used to build the predictive model for IOP after LASIK. The IOP constant was calculated by subtracting the predicted IOP from preoperative IOP. The paired samples t test, Pearson’s correlation analysis, curve estimation analysis, and linear regression analysis were used to evaluate the study data.

Results

The study included 425 eyes in 214 patients with a mean age of 32 ± 7.8 years. Mean spherical equivalent of the attempted correction (SE-ac) was −3.7 ± 1.7 diopters. Mean post-LASIK decrease in IOP was 4.6 ± 2.3 mmHg. The difference between preoperative and postoperative IOP was statistically significant (P < 0.001). SE-ac, preoperative IOP, and central corneal thickness had highly significant effects on postoperative IOP, based on linear regression analysis (P < 0.001 and R 2 = 0.043, P < 0.001 and R 2 = 0.370, and P < 0.001 and R 2 = 0.132, respectively). Regression model was created (F = 127.733, P < 0.001), and the adjusted R 2 value was 0.548.

Conclusions

Evaluation of IOP after LASIK is important in myopic patients. The present study described a practical formula for predicting the true IOP with the aid of an IOP constant value in myopic eyes following LASIK.

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Acknowledgements

The authors thank statistician Ceyda Afacan, Mimar Sinan Fine Arts University, Institute of Science and Technology, Department of Statistics, Istanbul, Turkey, and language editor Scott B. Evans, MSW, Ankara, Turkey.

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Authors and Affiliations

  1. Department of Ophthalmology, Acibadem University School of Medicine, Acibadem Maslak Hastanesi Goz Hastaliklari Klinigi, Darussafaka Mah. Buyukdere Cad. No:40 34457, Sariyer, Istanbul, Turkey

    Ayse Ebru Bahadir Kilavuzoglu & Cemile Banu Cosar

  2. Umraniye Training and Research Hospital, Eye Clinic, Elmalikent Mah. Adem Yavuz Cad. No:1 34764, Umraniye, Istanbul, Turkey

    Tahir Kansu Bozkurt

  3. Etiler Dunya Goz Hospital, Yanarsu Sk. No:1 34337, Etiler, Istanbul, Turkey

    Asım Bozkurt Sener

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  1. Ayse Ebru Bahadir Kilavuzoglu
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  2. Tahir Kansu Bozkurt
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  3. Cemile Banu Cosar
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  4. Asım Bozkurt Sener
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Correspondence to Ayse Ebru Bahadir Kilavuzoglu.

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Bahadir Kilavuzoglu, A.E., Bozkurt, T.K., Cosar, C.B. et al. A sample predictive model for intraocular pressure following laser in situ keratomileusis for myopia and an “intraocular pressure constant”. Int Ophthalmol 38, 1541–1547 (2018). https://doi.org/10.1007/s10792-017-0617-0

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  • DOI: https://doi.org/10.1007/s10792-017-0617-0

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