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Surgical removal of subfoveal choroidal neovascularization in pathologic myopia: a 12-year follow-up study

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Abstract

The purpose of this study was to review the 12-year visual outcomes of patients who underwent surgical removal for subfoveal choroidal neovascularization (CNV) attributable to pathologic myopia. This retrospective study included 14 patients, with a mean age of 45.8 years, high myopia (>6 D) and classic subfoveal CNV. They were treated with pars plana vitrectomy and surgical removal of CNV. All patients were followed up every 3 months for 2 years, with visual acuity (VA), fundus examination, and fluorescein angiography and then every year for 5 years. Ten patients underwent a final visit with VA and fundus examination after a minimum 12-year follow-up. The main outcome measurement was VA and the secondary outcome measurement was the lesion size. After 12 years of follow-up, the mean VA did not significantly change over time, with a mean gain of 0.22 logMAR at 1 year, and 0.18, 0.12 and 0.05 at 2, 5 and 12 years, respectively. The anatomical evolution was characterized by a significant enlargement of the lesion size at 5 years. This study showed that final VA after surgical treatment with 12 years of follow-up was poor, due to the significant CNV scar enlargement over time. These results should prompt a prospective randomized study of other medical treatments, particularly anti-vascular endothelial growth factor therapy.

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The authors have no proprietary or commercial interest in any materials discussed in this article.

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Authors and Affiliations

  1. Department of Ophthalmology, University Hospital of Grenoble, Joseph Fourier University, Grenoble 1, 38041, Grenoble, France

    R. Hera, C. Chiquet & J. P. Romanet

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  1. R. Hera
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  2. C. Chiquet
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  3. J. P. Romanet
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Correspondence to R. Hera.

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Hera, R., Chiquet, C. & Romanet, J.P. Surgical removal of subfoveal choroidal neovascularization in pathologic myopia: a 12-year follow-up study. Int Ophthalmol 33, 671–676 (2013). https://doi.org/10.1007/s10792-013-9761-3

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  • DOI: https://doi.org/10.1007/s10792-013-9761-3

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