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Mucuna sanjappae Aitawade et Yadav: a new species of Mucuna with promising yield of anti-Parkinson’s drug L-DOPA

  • Notes on Neglected and Underutilized Crops
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Abstract

Mucuna is a well-known medicinal and food plant widely exploited for its seed pods and leaves in many tropical countries. The drug L-3, 4-dihydroxyphenylalanine (L-DOPA) extracted from seeds of Mucuna plant has been commonly used in the treatment of Parkinson’s disease. In the present study, a new species of Mucuna, M. sanjappae Aitawade et Yadav from north-Western Ghats of India, has been analyzed for the presence of L-DOPA and a reasonable level of this drug (7.3 %) was detected. The necessary biochemical characterization of the seeds extract of this plant showed nutritional and anti-nutritional components. Simultaneously, moisture, ash, dietary fiber, calorific value, nitrate and mineral contents of seeds were also determined. This new plant species will be a potential candidate for extraction of L-DOPA and will be a good addition to the existing natural sources of anti-Parkinson’s drug since demand for L-DOPA is continuously escalating.

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Acknowledgments

We sincerely thank Department of Biotechnology, Government of India for “Interdisciplinary Programme of Life Sciences for Advanced Research and Education (IPLS)”, providing financial support to this work and fellowship to R. R. Patil and A. R. Gholave. V. A. Bapat thanks Indian National Science Academy, New Delhi for senior scientist fellowship.

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Authors and Affiliations

  1. Department of Biochemistry, Shivaji University, Kolhapur, 416 004, India

    R. R. Patil & J. P. Jadhav

  2. Department of Biotechnology, Shivaji University, Vidyanagar, Kolhapur, 416 004, India

    R. R. Patil, J. P. Jadhav & V. A. Bapat

  3. Department of Botany, Shivaji University, Kolhapur, 416 004, India

    A. R. Gholave & S. R. Yadav

Authors
  1. R. R. Patil
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  2. A. R. Gholave
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  3. J. P. Jadhav
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  4. S. R. Yadav
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  5. V. A. Bapat
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Correspondence to J. P. Jadhav.

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Patil, R.R., Gholave, A.R., Jadhav, J.P. et al. Mucuna sanjappae Aitawade et Yadav: a new species of Mucuna with promising yield of anti-Parkinson’s drug L-DOPA. Genet Resour Crop Evol 62, 155–162 (2015). https://doi.org/10.1007/s10722-014-0164-8

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