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Absence of ocular interaction in flicker ERG responses reflecting cone opponent and luminance signals

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Abstract

The aim of the study was to investigate whether there is an ocular interaction in the flicker ERG responses reflecting luminance and cone opponency in normal human subjects. Flicker ERGs were recorded from one dilated eye of 10 healthy volunteers. Each subject was tested twice: once with and once without occluding the opposite eye. Red and green LEDs were modulated in counterphase in a Ganzfeld stimulator. ERG responses were recorded for different ratios of the modulation in the red and green LEDs and at 12 and 36 Hz. The amplitudes and phases of the fundamental components were compared between the conditions with and without occlusion. The 12-Hz flicker ERGs reflected activity of the cone opponent channel, whereas the 36-Hz data reflected luminance activity. There were no significant differences between the conditions with and without occluding the opposite eye for any of the stimulus protocols. Ocular interaction is absent in flicker ERGs reflecting cone opponent and luminance activity.

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Acknowledgments

The work was supported by German Research Council (DFG) grant KR1317/9-1 and CAPES/DAAD PROBRAL grant #182/2007. MTSB had a doctoral FAPESP fellowship (07/55125-1). DFV is a CNPq Research Fellow. JK is Fellow in the Excellence Program of the Hertie Foundation.

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Authors and Affiliations

  1. Department of Ophthalmology, University Hospital Erlangen, Erlangen, Germany

    Mirella Telles Salgueiro Barboni & Jan Kremers

  2. Center of Neuroscience and Behavior, University of Sao Paulo, Sao Paulo, Brazil

    Mirella Telles Salgueiro Barboni & Dora Fix Ventura

  3. Department of Experimental Psychology, University of Sao Paulo, Sao Paulo, Brazil

    Mirella Telles Salgueiro Barboni & Dora Fix Ventura

  4. Department of Ophthalmology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany

    Jan Kremers

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  1. Mirella Telles Salgueiro Barboni
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  2. Dora Fix Ventura
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  3. Jan Kremers
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Correspondence to Jan Kremers.

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Barboni, M.T.S., Ventura, D.F. & Kremers, J. Absence of ocular interaction in flicker ERG responses reflecting cone opponent and luminance signals. Doc Ophthalmol 121, 69–75 (2010). https://doi.org/10.1007/s10633-010-9229-y

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  • DOI: https://doi.org/10.1007/s10633-010-9229-y

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