Abstract
We prospectively assessed the relationship between nodular gastritis and Helicobacter pylori infection. Of 1409 adults who underwent endoscopy for persistent dyspepsia between June 2004 and August 2005, 41 (2.9%) patients were diagnosed with nodular gastritis (11 [27%] men and 30 [73%] women). The mean age was 45.9 years. A control group of 65 patients without nodular gastritis was also evaluated. The prevalence of H. pylori infection was higher in patients with nodular gastritis than in controls (38/41 [93%] vs. 33/65 [51%]). Of 21 patients treated to eradicate H. pylori, the nodular gastritis pattern resolved or improved in 16 patients on subsequent endoscopy. This study suggests that a nodular pattern of the gastric mucosa on endocscopy is a good indicator for H. pylori infection in adults, with the high positive predictive value of 92.7%.
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The authors would like to thank Dr. Mary Jeanne Buttrey for critical reading and correction of the manuscript.
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Chen, MJ., Wang, TE., Chang, WH. et al. Nodular Gastritis: An Endoscopic Indicator of Helicobacter Pylori Infection. Dig Dis Sci 52, 2662–2666 (2007). https://doi.org/10.1007/s10620-006-9281-3
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DOI: https://doi.org/10.1007/s10620-006-9281-3