Furostanol and spirostanol glycosides 1 and 2 were isolated from the flowers of Allium leucanthum, a Caucasian endemic species that grows in Georgia. The structures were established on the base of chemical evidence and spectral analyses ( 1 H, 13 C NMR, 1 H– 1 H COSY, 1 H– 13 C COSY, HMBC, and HR-MS) data. Compound 1 (leucofuranoside A) was reported for the first time and was identified as 26-O-β-Dglucopyranosyl-(25R)-5α-furostane-3β,6β-diol-3-O-β-D-glucopyranosyl-(1→2)-O-β-D-xylopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside. Compound 2 was identified as (25R)-5α-spirostane-3β,6β-diol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside and described for the first time in the genus Allium.
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Acknowledgment
The authors are grateful for the support of the French Embassy in Georgia. We thank Prof. Jumber Kuchukhidze for identification of Allium leucanthum K. Koch, and Gilbert Boudon for his technical support. This research was partially supported by the program Shota Rustaveli National Science Foundation “Research Grants for Young Scientists 2013” (Grant Agreement Nr. YS/1/8-404/13).
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2015, pp. 772–775.
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Mskhiladze, L., Chincharadze, D., Mshvildadze, V. et al. Steroidal Glycosides from the Flowers of Allium leucanthum . Chem Nat Compd 51, 900–904 (2015). https://doi.org/10.1007/s10600-015-1444-z
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DOI: https://doi.org/10.1007/s10600-015-1444-z