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Colchicinoids from the Seeds of Colchicum umbrosum

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Chemistry of Natural Compounds Aims and scope

A new colchicinoid from the seeds of Colchicum umbrosum (Colchicaceae) has been isolated and identified as 4-hydroxycolchicine (6) together with seven known colchicinoids as colchicine (1), N-deacetyl-N-formylcolchicine (2), colchifoline (3), colchicilline (4), 3-demethylcolchicine (5), demecolcine (7), and colchicoside (8).

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Acknowledgment

Professor Ali H. Mericli thanks the Alexander von Humboldt Foundation (Germany) for a fellowship and the authors thank Prof. Dr. Alexandra K. Kiemer and Dr. Josef Zapp (Department of Pharmaceutical Biology, Saarland University, Saarbrucken, Germany) for some NMR measurements.

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Authors and Affiliations

  1. Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, 34116, Beyazit, Istanbul, Turkey

    Nurhayat Sutlupinar & Tuba Kilincli

  2. Department of Pharmacognosy, Faculty of Pharmacy, Near East University Nicosia, Northern Cyprus, Mersin, 10, Turkey

    Ali H. Mericli

Authors
  1. Nurhayat Sutlupinar
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  2. Tuba Kilincli
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  3. Ali H. Mericli
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Corresponding author

Correspondence to Ali H. Mericli.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2015, pp. 445–447.

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Sutlupinar, N., Kilincli, T. & Mericli, A.H. Colchicinoids from the Seeds of Colchicum umbrosum . Chem Nat Compd 51, 512–514 (2015). https://doi.org/10.1007/s10600-015-1326-4

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  • DOI: https://doi.org/10.1007/s10600-015-1326-4

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