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Lipids from the Aerial Part of Scutellaria ramosissima

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Chemistry of Natural Compounds Aims and scope

Total lipids (TL) (2.1%), more than half of which were glycolipids (GL) (1.3%), and neutral lipids (NL) (0.54%) and phospholipids (PL) (0.26%) were isolated from the air-dried aerial part of Scutellaria ramosissima. The principal acids of the NL were 16:0, 18:2, and 18:3. Acid 16:0 (up to 40 mass% of the acids) dominated the glycolipids. Palmitic and linoleic acids dominated the PL with 18:1 in combination with 18:3 comprising slightly greater than 31%, like linoleic acid. The chlorophyll content was 197.3 mg% in the total lipids; carotinoids, 157.1 mg%; tocopherols, 357.0 mg% in unsaponified substances (US). The cytotoxic activity of the S. ramosissima lipid fractions was tested on HL-60 and HeLa cancer cell lines using the MTT test. PL, NL, and US showed cytotoxicity for HL-60 cells with IC50 values of 8.3, 22.0, and 24.3 μg/mL, respectively, and were inactive for HeLa cells. The GL and TL turned out to be slightly active.

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References

  1. Flora of the USSR [in Russian], Vol. 20, Moscow-Leningrad, 1954, p. 122.

  2. Flora of Uzbekistan [in Russian], Vol. 5, Tashkent, 1961, pp. 263-416.

  3. K. Kh. Khodzhimatov, G. S. Aprasidi, and A. K. Khodzhimatov, Wild Medicinal Plants of Central Asia [in Russian], Fan, Tashkent, 1995, pp. 83–98.

    Google Scholar 

  4. P. Parajuli, N. Joshee, A. M. Rimando, S. Mittal, and A. K. Yadav, Planta Med., 75, 41 (2009).

    Article  CAS  PubMed  Google Scholar 

  5. M. P. Yuldashev, E. Kh. Batirov, and V. M. Malikov, Chem. Nat. Compd., 28, 151 (1992).

    Article  Google Scholar 

  6. M. P. Yuldashev, E. Kh. Batirov, A. Nigmatullaev, and V. M. Malikov, Chem. Nat. Compd., 30, 324 (1994).

    Article  Google Scholar 

  7. M. P. Yulgashev, E. Kh. Batirov, and V. M. Malikov, Chem. Nat. Compd., 31, 264 (1995).

    Article  Google Scholar 

  8. N. Z. Mamadalieva, F. Herrmann, M. Z. El-Readi, A. Tahrani, R. Hamoud, D. Egamberdieva, S. S. Azimova, and M. Wink, J. Pharm. Pharmacol., 63, 1346 (2011).

    Article  CAS  PubMed  Google Scholar 

  9. J. Folch, M. Lees, and J. H. Sloane-Stanley, J. Biol. Chem., 226, 197 (1957).

    Google Scholar 

  10. N. K. Yuldasheva, N. T. Ulchenko, S. D. Gusakova, and A. I. Glushenkova, in: Abstracts of the 3rd International Symposium on Edible Plant Resources and the Bioactive Ingredients, Urumqi, China, July 28-August 1, 2012, p. 134.

  11. M. Kates, Techniques of Lipidology: Isolation, Analysis, and Identification of Lipids, Elsevier, New York, 1972.

    Google Scholar 

  12. E. J. Weber, J. Am. Oil Chem. Soc., 47, 340 (1970).

    Article  CAS  PubMed  Google Scholar 

  13. Handbook of Study Methods, Technochemical Control and Production Accounting in the Oil-Fat Industry [in Russian], Vol. 1, Book 2, 1967, a) p. 815; b) p. 822.

  14. V. V. Polevoi (ed.), Methods of Biochemical Analysis of Plants [in Russian], Leningrad, 1978, p. 92.

  15. Appendix to the USSR State Pharmacopoeia [in Russian], Vol. 3, Xth Ed., Moscow, 1986, p. 321.

  16. N. T. Ul’chenko, N. P. Bekker, and A. I. Glushenkova, Chem. Nat. Compd., 36, 572 (2000).

    Article  Google Scholar 

  17. L. F. Fieser and M. Fieser, Reagents for Organic Synthesis, Wiley, New York, 1967.

    Google Scholar 

  18. T. Mosmann, J. Immunol. Methods, 65, 55 (1983).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    N. K. Yuldasheva, N. T. Ul’chenko, N. Mamadalieva & A. I. Glushenkova

  2. Department for Innovation in Biological, Agro-food and Forestal Systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell’Universita, Blocco D, 01100, Viterbo, Italy

    E. Ovidi, D. Triggiani & A. Tiezzi

Authors
  1. N. K. Yuldasheva
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  2. N. T. Ul’chenko
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  3. N. Mamadalieva
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  4. A. I. Glushenkova
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  5. E. Ovidi
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  6. D. Triggiani
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  7. A. Tiezzi
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Correspondence to N. K. Yuldasheva.

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Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2014, pp. 64–66.

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Yuldasheva, N.K., Ul’chenko, N.T., Mamadalieva, N. et al. Lipids from the Aerial Part of Scutellaria ramosissima . Chem Nat Compd 50, 68–71 (2014). https://doi.org/10.1007/s10600-014-0868-1

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  • DOI: https://doi.org/10.1007/s10600-014-0868-1

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