Phytochemical profiling of the n-BuOH extract of the culture broth of the thermotolerant polyester-degrading actinomycete Actinomadura miaoliensis BCRC 16873 by a combination of liquid/liquid extraction, column chromatography, and preparative TLC afforded one new γ-lactone, namely actinomiaolone (1), along with seven known compounds, 3,4-methylenedioxy-5-methoxycinnamyl alcohol (2), myristic acid (3), casticin (4), (+)-glaberide I (5), (+)-syringaresinol (6), (+)-yangambin (7), and trans-cinnamaldehyde (8). The structures were established by extensive spectroscopic analyses, including 1D and 2D NMR (COSY, HSQC, and HMBC), and HR-ESI-MS, and by comparison with published data.
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Acknowledgment
This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China (Grant No. 94-EC-17-A-17-R7-0563). The authors also thank Senior Technician Ms. Chyi-Jia Wang of the Center for Resources, Research, and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2013, pp. 196–198.
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Cheng, MJ., Tseng, M., Yuan, GF. et al. Phytochemical investigation of the culture broth of actinomycete Actinomadura miaoliensis BCRC 16873. Chem Nat Compd 49, 226–228 (2013). https://doi.org/10.1007/s10600-013-0567-3
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DOI: https://doi.org/10.1007/s10600-013-0567-3