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Derivatives of the alkaloid convolvine and their pharmacological activity

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Chemistry of Natural Compounds Aims and scope

A series of new convolvine derivatives based on the alkaloid from Convolvulus subhirsutus and C. pseudocanthabrica were synthesized using alkylhalides and aliphatic and aromatic acid chlorides. Results of biological tests showed that convolvine and its derivatives exhibited pronounced antihypoxic, immunomodulating, and anti-inflammatory activity.

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Authors and Affiliations

  1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, 100170, Tashkent

    A. M. Gapparov, I. I. Okhunov, S. F. Aripova, A. Nabiev & V. U. Khuzhaev

Authors
  1. A. M. Gapparov
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  2. I. I. Okhunov
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  3. S. F. Aripova
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  4. A. Nabiev
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  5. V. U. Khuzhaev
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Corresponding author

Correspondence to S. F. Aripova.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2011, pp. 539–541.

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Gapparov, A.M., Okhunov, I.I., Aripova, S.F. et al. Derivatives of the alkaloid convolvine and their pharmacological activity. Chem Nat Compd 47, 608–611 (2011). https://doi.org/10.1007/s10600-011-0007-1

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  • DOI: https://doi.org/10.1007/s10600-011-0007-1

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