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Estrogen activity of terpenoids from plants of the genus Ferula

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Chemistry of Natural Compounds Aims and scope

The relationship between chemical structure and estrogen activity of a series of terpenoid esters with aromatic and aliphatic acids was studied. The studied compounds were isolated from the underground and aerial organs of Ferula tenuisecta, F. akitschkensis, F. lapidosa, F. juniperina, F. ceratophylla, F. pallida, F. tschimganica, and F. prangifolia. The estrogen activity was determined in vivo tests at a dose of 1 mg/kg.

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References

  1. A. G. Kurmukov and Kh. S. Akhmedkhodzhaeva, Estrogen Medicinal Preparations from Plants of the Genus Ferula [in Russian], Ibn-Sino, Tashkent (1994).

  2. G. Appendino, P. Spagliardi, O. Sterner, and S. Milligan, J. Nat. Prod., 67, 1557 (2004).

    Article  PubMed  CAS  Google Scholar 

  3. L. A. Golovina and A. I. Saidkhodzhaev, Khim. Prir. Soedin., 318 (1981).

  4. L. A. Golovina, A. I. Saidkhodzhaev, N. D. Abdullaev, V. M. Malikov, and M. R. Yagudaev, Khim. Prir. Soedin., 296 (1983).

  5. L. A. Golovina, A. I. Saidkhodzhaev, V. M. Malikov, and S. Melibaev, Khim. Prir. Soedin., 787 (1982).

  6. L. A. Golovina, A. I. Saidkhodzhaev, and V. M. Malikov, Khim. Prir. Soedin., 301 (1983).

  7. A. Yu. Kushmuradov, A. I. Saidkhodzhaev, and A. Sh. Kadyrov, Khim. Prir. Soedin., 523 (1981).

  8. A. Yu. Kushmuradov, A. I. Saidkhodzhaev, and A. Sh. Kadyrov, Khim. Prir. Soedin., 400 (1981).

  9. A. Yu. Kushmuradov, M. K. Makhmudov, A. I. Saidkhodzhaev, B. Tashkhodzhaev, V. M. Malikov, and M. R. Yagudaev, Khim. Prir. Soedin., 42 (1990).

  10. A. I. Saidkhodzhaev, Khim. Prir. Soedin., 70 (1978).

  11. A. Sh. Kadyrov, A. I. Saidkhodzhaev, G. K. Nikonov, and U. Rakhmankulov, Khim. Prir. Soedin., 284 (1977).

  12. A. I. Saidkhodzhaev and G. K. Nikonov, Khim. Prir. Soedin., 559 (1972).

  13. T. Kh. Khasanov, A. I. Saidkhodzhaev, and G. K. Nikonov, Khim. Prir. Soedin., 528 (1974).

  14. A. I. Saidkhodzhaev and G. K. Nikonov, Khim. Prir. Soedin., 105 (1976).

  15. A. I. Saidkhodzhaev and G. K. Nikonov, Khim. Prir. Soedin., 28 (1973).

  16. G. V. Sagitdinova and A. I. Saidkhodzhaev, Khim. Prir. Soedin., 790 (1977).

  17. L. A. Golovina and A. I. Saidkhodzhaev, Khim. Prir. Soedin., 796 (1977).

  18. G. V. Sagitdinova, A. I. Saidkhodzhaev, and V. M. Malikov, Khim. Prir. Soedin., 864 (1979).

  19. G. V. Sagitdinova, A. I. Saidkhodzhaev, and V. M. Malikov, Khim. Prir. Soedin., 809 (1978).

  20. A. Sh. Kadyrov and G. K. Nikonov, Khim. Prir. Soedin., 59 (1972).

  21. A. I. Saidkhodzhaev, N. D. Abdullaev, T. Kh. Khasanov, G. K. Nikonov, and M. R. Yagudaev, Khim. Prir. Soedin., 519 (1977).

  22. S. K. Rami and L. H. Claude, Reprod. Toxicol., 2, No. 2, 81 (1989).

    Google Scholar 

  23. P. V. Sergeev and V. I. Petrov, Receptors [in Russian], Moscow (1999).

  24. L. A. Golovina, T. Kh. Khasanov, A. I. Saidkhodzhaev, V. M. Malikov, and U. Rakhmankulov, Khim. Prir. Soedin., 566 (1978).

  25. B. Tashkhodzhaev, “Molecular structure of several natural sesquiterpenoid and diterpenoid alkaloids from x-ray structure analyses and molecular mechanics,” Author’s Abstract of a Doctroal Dissertation in Chemical Sciences, Tashkent (1998).

  26. G. Chernaev, T. Barkova, and V. J. Egorova, Steroid Biochem., 6, 1483 (1978).

    Article  Google Scholar 

  27. N. A. Yudaev, Biochemistry of Hormones and Hormonal Regulation, Mir, Moscow (1976), p. 145.

  28. N. D. Fanchenco, S. V. Sturchak, and R. N. Shchedrina, Acta Endocrinol., 90, 167 (1979).

    Google Scholar 

  29. J. Evans, F. Roger, R. Varney, and F. Koch, Endocrinology, 28, No. 6, 747 (1944).

    Google Scholar 

  30. E. Allen and E. Dosy, J. Am. Med. Assoc., 81, 819 (1923).

    CAS  Google Scholar 

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Authors and Affiliations

  1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Uzbekistan, Tashkent

    S. S. Nazrullaev, A. I. Saidkhodzhaev, Kh. S. Akhmedkhodzhaeva, V. N. Syrov, B. F. Rasulev & Z. A. Khushbaktova

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  1. S. S. Nazrullaev
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  2. A. I. Saidkhodzhaev
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  3. Kh. S. Akhmedkhodzhaeva
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  4. V. N. Syrov
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  5. B. F. Rasulev
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  6. Z. A. Khushbaktova
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Correspondence to Z. A. Khushbaktova.

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Translated fromKhimiya Prirodnykh Soedinenii, No. 5, pp. 463–467, September-October, 2008.

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Nazrullaev, S.S., Saidkhodzhaev, A.I., Akhmedkhodzhaeva, K.S. et al. Estrogen activity of terpenoids from plants of the genus Ferula . Chem Nat Compd 44, 572–577 (2008). https://doi.org/10.1007/s10600-008-9143-7

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  • DOI: https://doi.org/10.1007/s10600-008-9143-7

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