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Bacillomycin D from the Marine Isolate of Bacillus subtilis KMM 1922

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Abstract

Strain KMM 1922 of Bacillus subtilis, a producer of the antifungal iturin peptide antibiotic bacillomycin D, was isolated from a specimen of the Kuril sponge Stelletta validissima. The structure of the compound was proved using two-dimensional NMR spectroscopy, tandem electrospray mass spectrometry, and literature data. The peptide was shown to exhibit a pH-dependent cytotoxic activity.

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Authors and Affiliations

  1. Pacific Institute of Bioorganic Chemistry, Far East Division, Russian Academy of Sciences, 690022, Vladivostok, Russia

    G. K. Oleinikova, V. G. Voinov, E. L. Chaikina, L. S. Shevchenko & T. A. Kuznetsova

  2. Santori Institute of Bioorganic Research, 1-1-1 Shimamoto, Mishima, Osaka, 618-8503, Japan

    A. S. Dmitrenok

Authors
  1. G. K. Oleinikova
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  2. A. S. Dmitrenok
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  3. V. G. Voinov
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  4. E. L. Chaikina
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  5. L. S. Shevchenko
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  6. T. A. Kuznetsova
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Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 373–375, July–August, 2005.

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Oleinikova, G.K., Dmitrenok, A.S., Voinov, V.G. et al. Bacillomycin D from the Marine Isolate of Bacillus subtilis KMM 1922. Chem Nat Compd 41, 461–464 (2005). https://doi.org/10.1007/s10600-005-0177-9

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  • DOI: https://doi.org/10.1007/s10600-005-0177-9

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