A new method is proposed for the production of derivatives of thieno[2,3-b]pyrrole on the basis of acid-catalyzed recyclization of the furan ring in 2-R-amino-3-furfurylthiophenes. It was established that the direction of the transformations occurring under the influence of a mixture of hydrochloric and acetic acids and also the structure of the obtained compounds depend on the nature of the protecting group.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 33–41, January, 2011.
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Stroganova, T.A., Vasilin, V.K. & Elizarova, E.A. Opening of the furan ring in 2-R-amino- 3-furfurylthiophenes by the action of acids. Chem Heterocycl Comp 47, 22–28 (2011). https://doi.org/10.1007/s10593-011-0715-2
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DOI: https://doi.org/10.1007/s10593-011-0715-2