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Repetitive Profound Thrombocytopenia After Treatment with Tirofiban: A Case Report

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Summary

The GPIIb/IIIa inhibitors are used in the acute coronary syndromes and interventional cardiology as antiplatelet agents. These drugs induce thrombocytopenia in approximately 1–5% of patients. Thrombocytopenia is rapid in onset and antibody mediated. Abciximab is associated with higher incidence of thrombocytopenia than eptifibatide and tirofiban. Profound thrombocytopenia has reportedly been an issue with abciximab, but not with tirofiban. We reported a case of acute profound thrombocytopenia due to on tirofiban treatment in the same patient at two different times.

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Authors and Affiliations

  1. Cardiology Department, Medical Faculty, Yüzüncü Yil University, Van, Turkey

    Beyhan Eryonucu (Dr.), Mustafa Tuncer & Reha Erkoc

  2. Yüzüncü YilÜniversitesi, Tip Fakültesi Kardiyoloji AD, 65200, Van-Türkiye

    Beyhan Eryonucu (Dr.)

Authors
  1. Beyhan Eryonucu
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  2. Mustafa Tuncer
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  3. Reha Erkoc
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Correspondence to Beyhan Eryonucu.

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Eryonucu, B., Tuncer, M. & Erkoc, R. Repetitive Profound Thrombocytopenia After Treatment with Tirofiban: A Case Report. Cardiovasc Drugs Ther 18, 503–505 (2004). https://doi.org/10.1007/s10557-004-6228-9

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  • DOI: https://doi.org/10.1007/s10557-004-6228-9

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