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Simple prediction of right ventricular ejection fraction using tricuspid annular plane systolic excursion in pulmonary hypertension

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Abstract

The present study examined whether tricuspid annular plane systolic excursion (TAPSE) can simply predict right ventricular ejection fraction (RVEF) in patients with pulmonary hypertension (PH). The TAPSE cut-off value to predict reduced RVEF was also evaluated. The association between TAPSE and cardiac magnetic resonance imaging (CMRI)-derived RVEF was examined in 53 PH patients. The accuracy of the prediction equation to calculate RVEF using TAPSE was also evaluated. In PH patients, TAPSE was strongly correlated with CMRI-derived RVEF in PH patients (r = 0.86, p < 0.0001). We then examined the accuracy of the two equations: the original regression equation (RVEF = 2.01 × TAPSE + 0.6) and the simplified prediction equation (RVEF = 2 × TAPSE). Bland–Altman plot showed that the mean difference ± limits of agreement was 0.0 ± 10.6 for the original equation and −0.6 ± 10.6 for the simplified equation. Intraclass correlation coefficient was 0.84 for the original and 0.82 for the simplified equation. Normal RVEF was considered to be ≥40 % based on the data from 53 matched controls, and the best TAPSE cut-off value to determine reduced RVEF (<40 %) was calculated to be 19.7 mm (sensitivity 88.9 %, specificity 84.6 %). A simple equation of RVEF = 2 × TAPSE enables easy prediction of RVEF using TAPSE, an easily measurable M-mode index of echocardiography. TAPSE of 19.7 mm predicts reduced RVEF in PH patients with clinically acceptable sensitivity and specificity.

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Authors and Affiliations

  1. First Department of Medicine, Hokkaido University Hospital, North 14, West 5, Kita-ku, Sapporo, 060-8648, Japan

    Takahiro Sato, Ichizo Tsujino, Hiroshi Ohira, Asuka Yamada, Chisa Takashina & Taku Watanabe

  2. Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan

    Noriko Oyama-Manabe

  3. Department of Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    Yoichi M. Ito

  4. Department of Radiological Technology, Hokkaido University Hospital, Sapporo, Japan

    Hiroyuki Sugimori

  5. First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan

    Ichizo Tsujino & Masaharu Nishimura

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  1. Takahiro Sato
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  2. Ichizo Tsujino
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  3. Noriko Oyama-Manabe
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  4. Hiroshi Ohira
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  8. Chisa Takashina
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  9. Taku Watanabe
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  10. Masaharu Nishimura
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Correspondence to Ichizo Tsujino.

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Sato, T., Tsujino, I., Oyama-Manabe, N. et al. Simple prediction of right ventricular ejection fraction using tricuspid annular plane systolic excursion in pulmonary hypertension. Int J Cardiovasc Imaging 29, 1799–1805 (2013). https://doi.org/10.1007/s10554-013-0286-7

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  • DOI: https://doi.org/10.1007/s10554-013-0286-7

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