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A comparison of visual and quantitative assessment of left ventricular ejection fraction by cardiac magnetic resonance

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An Erratum to this article was published on 08 April 2011

Abstract

To determine the accuracy of visual analysis of left ventricular (LV) function in comparison with the accepted quantitative gold standard method, Cardiac Magnetic Resonance (CMR). Cine CMR imaging was performed at 1.5 T on 44 patients with a range of ejection fractions (EF, 5–80%). Clinicians (n = 18) were asked to visually assess EF after sequentially being shown cine images of a four chamber (horizontal long axis; HLA), two chamber (vertical long axis; VLA) and a short axis stack (SAS) and results were compared to a commercially available analysis package. There were strong correlations between visual and quantitative assessment. However, the EF was underestimated in all categories (by 8.4% for HLA, 8.4% for HLA + VLA and 7.9% for HLA + VLA + SAS, P all < 0.01) and particularly underestimated in mild LV impairment (17.4%, P < 0.01), less so for moderate (4.9%) and not for severe impairment (1%). Assessing more than one view of the heart improved visual assessment of LV, EF, however, clinicians underestimated EF by 8.4% on average, with particular inaccuracy in those with mild dysfunction. Given the important clinical information provided by LV assessment, quantitative analysis is recommended for accurate assessment.

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Abbreviations

EF:

Ejection fraction

HLA:

Horizontal long axis

SA:

Short axis

LV:

Left ventricle

VLA:

Vertical long axis

CMR:

Cardiac magnetic resonance

References

  1. Bardy GH et al (2005) Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 352(3):225–237

    Article  PubMed  CAS  Google Scholar 

  2. Moss AJ et al (2002) Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 346(12):877–883

    Article  PubMed  Google Scholar 

  3. Linde C et al (2002) Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study. J Am Coll Cardiol 40(1):111–118

    Article  PubMed  Google Scholar 

  4. Corsia C et al (2004) Computerized quantification of left ventricular volumes on cardiac magnetic resonance images by level set method. Int Congr Ser 1268:1114–1119

    Article  Google Scholar 

  5. Basilico FC et al (1981) Non-invasive measurement of left ventricular function in coronary artery disease. Comparison of first pass radionuclide ventriculography, M-mode echocardiography, and systolic time intervals. Br Heart J 45(4):369–375

    Article  PubMed  CAS  Google Scholar 

  6. Galasko GI et al (2001) A prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction. Heart 86(3):271–276

    Article  PubMed  CAS  Google Scholar 

  7. Sievers B et al (2005) Visual estimation versus quantitative assessment of left ventricular ejection fraction: a comparison by cardiovascular magnetic resonance imaging. Am Heart J 150(4):737–742

    Article  PubMed  Google Scholar 

  8. Mueller X et al (1991) Subjective visual echocardiographic estimate of left ventricular ejection fraction as an alternative to conventional echocardiographic methods: comparison with contrast angiography. Clin Cardiol 14(11):898–902

    Article  PubMed  CAS  Google Scholar 

  9. Shih T, Lichtenberg R, Jacobs W (2003) Ejection fraction: subjective visual echocardiographic estimation versus radionuclide angiography. Echocardiography 20(3):225–230

    Article  PubMed  Google Scholar 

  10. Rider OJ et al (2009) Determinants of left ventricular mass in obesity; a cardiovascular magnetic resonance study. J Cardiovasc Magn Reson 11(1):9

    Article  PubMed  Google Scholar 

  11. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1(8476):307–310

    Article  PubMed  CAS  Google Scholar 

  12. Altman DG (2000) Diagnostic tests. In: Altman DG et al (eds) Statistics with confidence, British Medical Journal, London, UK

  13. Hendel RC et al (2009) ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 appropriate use criteria for cardiac radionuclide imaging: a report of the American College of Cardiology Foundation appropriate use criteria task force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine: endorsed by the American College of Emergency Physicians. Circulation 119(22):e561–e587

    Article  PubMed  Google Scholar 

  14. Rich S et al (1982) Determination of left ventricular ejection fraction by visual estimation during real-time two-dimensional echocardiography. Am Heart J 104(3):603–606

    Article  PubMed  CAS  Google Scholar 

  15. Akinboboye O et al (1995) Visual estimation of ejection fraction by two-dimensional echocardiography: the learning curve. Clin Cardiol 18(12):726–729

    Article  PubMed  CAS  Google Scholar 

  16. Bansal S, Vacek JL, Ehler D (2002) Consistency of echocardiographic ejection fraction: variation and ‘drift’ by interpreter and practice site. Eur J Echocardiogr 3(1):44–46

    Article  PubMed  CAS  Google Scholar 

  17. Cook DJ (1990) Clinical assessment of central venous pressure in the critically ill. Am J Med Sci 299(3):175–178

    Article  PubMed  CAS  Google Scholar 

  18. Stamm RB et al (1982) Two-dimensional echocardiographic measurement of left ventricular ejection fraction: prospective analysis of what constitutes an adequate determination. Am Heart J 104(1):136–144

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The British Heart Foundation supported this work.

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There are no conflicts of interest to declare.

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Correspondence to Cameron J. Holloway.

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An erratum to this article can be found at http://dx.doi.org/10.1007/s10554-011-9864-8

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Holloway, C.J., Edwards, L.M., Rider, O.J. et al. A comparison of visual and quantitative assessment of left ventricular ejection fraction by cardiac magnetic resonance. Int J Cardiovasc Imaging 27, 563–569 (2011). https://doi.org/10.1007/s10554-010-9706-0

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