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Transcriptional regulation of salinity stress: role and spatio-temporal expressions of ion-transporter gene promoters

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Biologia Plantarum

Abstract

Ion transporters play an important role in ion homeostasis and control ion flow from its intrusion to exclusion in the entire plant system. Abiotic stress tolerance in plants depends immensely on the activity of these transporters. The transporter proteins are transcriptionally regulated by cis-elements present in their upstream region for specific activity. The presence of different cis-elements facilitates cross-talk between different signal transduction pathways. Depending on the cis-elements, a specific stress signalling pathway is activated, eliciting a physiological change towards maintaining ion homeostasis to alleviate stress. Beta-glucuronidase localization studies using various promoter regions indicated their expression specificity in organs/tissues. This review gives an overview about promoter activity of different transporters and its involvement under salinity stress.

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Abbreviations

ABA:

abscisic acid

ABRE:

ABA responsive elements

GUS:

β-glucuronidase

HKT:

high affinity potassium transporter

MYB:

myeloblastosis

MYC:

myelocytomatosis

NHX:

sodium proton exchanger

TFs:

transcription factors

References

  • Adler, G., Blumwald, E., Bar-Zvi, D.: The sugar beet gene encoding the sodium/proton exchanger 1 (BvNHX1) is regulated by a MYB transcription factor. - Planta 232: 187–195, 2010.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Almeida, P., Katschnig, D., De Boer, A.H.: HKT transportersstate of the art. - Int. J. mol. Sci. 14: 20359–20385, 2013.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Apse, M.P., Aharon, G.S., Snedden, W.A., Blumwald, E.: Salt tolerance conferred by overexpression of a vacuolar Na+/H+ antiport in Arabidopsis. - Science 285: 1256–1258, 1999.

    Article  PubMed  CAS  Google Scholar 

  • Asins, M.J., Villalta, I., Aly, M.M., Olias, R., Alvarez de Morales, P., Huertas, R., Li, J., Jaime-Pérez, N., Haro, R., Raga, V., Carbonell, E.A., Belver, A.: Two closely linked tomato HKT coding genes are positional candidates for the major tomato QTL involved in Na+/K+ homeostasis. - Plant Cell Environ. 36: 1171–1191, 2013.

    Article  PubMed  CAS  Google Scholar 

  • Baek, D., Jiang, J., Chung, J.S., Wang, B., Chen, J., Xin, Z., Shi, H.: Regulated AtHKT1 gene expression by a distal enhancer element and DNA methylation in the promoter plays an important role in salt tolerance. - Plant Cell Physiol. 52: 149–161, 2011.

    Article  PubMed  CAS  Google Scholar 

  • Babgohari, M., Ebrahimie, E., Niazi, A.: In silico analysis of high affinity potassium transporter (HKT) isoforms in different plants. - Aquat. Biosyst. 10: 9, 2014.

    Article  CAS  Google Scholar 

  • Blumwald, E.: Sodium transport and salt tolerance in plants. - Curr. Opin. Cell Biol. 12: 431–434, 2000.

    Article  PubMed  CAS  Google Scholar 

  • Drozdowicz, Y.M., Kissinger, J.C., Rea, P.A.: AVP2, a sequence-divergent, K(+)-insensitive H(+)-translocating inorganic pyrophosphatase from Arabidopsis. - Plant Physiol. 123: 353–62, 2000.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Epstein, E.: Mineral nutrition of plants, principles and perspectives. - Bioscience 22: 739–739, 1972.

    Google Scholar 

  • Feki, K., Brini, F., Ben Amar, S., Saibi, W., Masmoudi, K.: Comparative functional analysis of two wheat Na+/H+ antiporter SOS1 promoters in Arabidopsis thaliana under various stress conditions. - J. appl. Genet. 56: 15–26, 2014.

    Article  PubMed  CAS  Google Scholar 

  • Fukuda, A., Nakamura, A., Hara, N., Toki, S., Tanaka, Y.: Molecular and functional analysis of rice NHX-type Na+/H+ antiporter genes. - Planta 233: 17–188, 2011.

    Article  CAS  Google Scholar 

  • Gao, C., Wang, Y., Liu, G., Wang, C., Jiang, J., Yang, C.: Cloning of ten peroxidase (POD) genes from Tamarix hispida and characterization of their responses to abiotic stress. - Plant mol. Biol. Rep. 28: 77, 2010.

    Article  CAS  Google Scholar 

  • Gao, C., Wang, Y., Jiang, B., Liu, G., Yu, L., Wei, Z., Yang, C.: A novel vacuolar membrane H+-ATPase c subunit gene (ThVHAc1) from Tamarix hispida confers tolerance to several abiotic stresses in Saccharomyces cerevisiae. - Mol. Biol. Rep. 38: 957–963, 2011.

    Article  PubMed  CAS  Google Scholar 

  • Gaxiola, R.A., Rao, R., Sherman, A., Grisafi, P., Alper, S.L., Fink, G.R.: The Arabidopsis thaliana proton transporters, AtNhx1 and Avp1, can function in cation detoxification in yeast. - Proc. nat. Acad. Sci. USA 96: 1480–1485, 1999.

    Article  PubMed  CAS  Google Scholar 

  • Gaxiola, R.A., Li, J., Undurraga, S., Dang, L.M., Allen, G.J., Alper, S.L., Fink, G.R.: Drought and salt-tolerant plants result from overexpression of the AVP1 H+-pump. - Proc. natl. Acad. Sci. USA 98: 11444–11449, 2001.

    Article  PubMed  CAS  Google Scholar 

  • Gaxiola, R.A., Fink, G.R., Hirschi, K.D.: Genetic manipulation of vacuolar proton pumps and transporters. - Plant Physiol. 129: 967–73, 2002.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Goyal, E., Singh, R.S., Kanika, K.: Isolation and functional characterization of salt overly sensitive 1 (SOS1) gene promoter from Salicornia brachiata. - Biol. Plant. 57: 465–473, 2013.

    Article  CAS  Google Scholar 

  • Hou, J., Jiang, P., Qi, S., Zhang, K., He, Q., Xu, C., Ding, Z., Zhang, K., Li, K.: Isolation and functional validation of salinity and osmotic stress inducible promoter from the maize type-II H+-pyrophosphatase gene by deletion analysis in transgenic tobacco plants. - PLoS ONE 11: e0154041, 2016.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kaur, C., Kumar, G., Kaur, S., Ansari, M.W., Pareek, A., Sopory, S.K., Singla-Pareek, S.L. Molecular cloning and characterization of salt overly sensitive gene promoter from Brassica juncea (BjSOS2). - Mol. Biol. Rep. 42: 1139–1148, 2015.

    Article  PubMed  CAS  Google Scholar 

  • Iida, K., Seki, M., Sakurai, T., Satou, M., Akiyama, K., Toyoda, T., Konagaya, A., Shinozaki, K.: RARTF, database and tools for complete sets of Arabidopsis transcription factors. - DNA Res. 12: 247–56, 2005.

    Article  PubMed  CAS  Google Scholar 

  • Löw, R., Rockel, B., Kirsch, M., Ratajczak, R., Hortensteiner, S., Martinoia, E., Lüttge, U., Rausch, T.: Early salt stress effects on the differential expression of vacuolar H+-ATPase genes in roots and leaves of Mesembryanthemum crystallinum. - Plant Physiol 110: 259–265, 1996.

    Article  PubMed  PubMed Central  Google Scholar 

  • Maser, P., Eckelman, B., Vaidyanathan, R., Horie, T., Fairbairn, D.J., Kubo, M., Yamagami, M., Yamaguchi, K., Nishimura, M., Uozumi, N., Robertson, W., Sussman, M.R., Schroeder, J.I.: Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disruption of the Na+ transporter AtHKT1. - FEBS Lett. 531: 157–161, 2002.

    Article  PubMed  CAS  Google Scholar 

  • Mewes, H.W., Albermann, K., Bähr, M. Frishman, D., Gleissner, A., Hani, J., Heumann, K., Kleine, K., Maierl, A., Oliver, S.G., Pfeiffer, F., Zollner, A.: Overview of the yeast genome. - Nature 387: 7–65, 1997.

    Article  PubMed  Google Scholar 

  • Mitsuda, N., Enami, K., Nakata, M., Takeyasuc, K., Sato, M.H.: Novel type Arabidopsis thaliana H+-PPase is localized to the Golgi apparatus. - FEBS Lett. 488: 29–33, 2001.

    Article  PubMed  CAS  Google Scholar 

  • Nass, R., Cunningham, K.W., Rao, R.: Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance. - J. biol. Chem. 272: 26145–26152, 1997.

    Article  PubMed  CAS  Google Scholar 

  • Nass, R., Rao, R.: Novel localization of a Na+/H+ exchanger in a late endosomal compartment of yeast. - J. biol. Chem. 273: 21054–21060,1998.

    Article  PubMed  CAS  Google Scholar 

  • Oh, D., Dassanayake, M., Haas, J.S. Kropornika, A., Wright, C., d'Urzo, M.P., Hong, H., Ali, S., Hernandez, A., Lambert, G.M., Inan, G., Galbraith, D.W., Bressan, R.A., Yun, D.J., Zhu, J.K., Cheeseman, J.M., Bohnert, H.J.: Genome structures and halophyte-specific gene expression of the extremophile Thellungiella parvula in comparison with Thellungiella salsuginea (Thellungiella halophila) and Arabidopsis. - Plant Physiol. 154: 1040–1052, 2010.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Platten, J.D., Cotsaftis, O., Berthomieu, P., Bohnert, H., Davenport, R.J., Fairbairn, D.J., Horie, T., Leigh, R.A., Lin, H.X., Luan, S., Mäser, P., Pantoja, O., Rodríguez-Navarro, A., Schachtman, D.P., Schroeder, J.I., Sentenac, H., Uozumi, N., Véry, A.A., Zhu, J.K., Dennis, E.S., Tester, M.: Nomenclature for HKT transporters, key determinants of plant salinity tolerance. - Trends Plant Sci. 11: 372–374, 2006.

    Article  PubMed  CAS  Google Scholar 

  • Potenza, C., Aleman, L., Sengupta-Gopalan, C.: Targeting transgene expression in research, agricultural and environmental applications. Promoters used in plant transformation. - in vitro cell. dev. Biol. Plant 40: 1–22, 2004.

    Article  CAS  Google Scholar 

  • Rea, P.A., Poole, R.J.: Proton-translocating inorganic pyrophosphatase in red beet (Beta vulgaris L.) tonoplast vesicles. - Plant Physiol. 77: 46–52, 1985.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Reynolds, P.H.S. (ed.): Inducible Gene Expression in Plants. - CABI Publishing, Oxon, 1999.

    Google Scholar 

  • Shi, H., Ishitani, M., Kim, C., Zhu, J.K.: The Arabidopsis thaliana salt tolerance gene SOS1 encodes a putative Na+/H+ antiporter. - Proc. nat. Acad. Sci. USA 97: 6896–6901, 2000.

    Article  PubMed  CAS  Google Scholar 

  • Shi, H., Quintero, F.J,, Pardo, J.M., Zhu, J.K.: The putative plasma membrane Na+/H+ antiporter SOS1 controls longdistance Na+ transport in plants. - Plant Cell 14: 465–477, 2002.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Shi, H., Zhu, J.K.: Regulation of expression of the vacuolar Na+/H+ antiporter gene AtNHX1 by salt stress and abscisic acid. - Plant mol. Biol. 50: 543–550, 2002.

    Article  PubMed  CAS  Google Scholar 

  • Sun, Q., Gao, F., Zhao, L., Li, K., Zhang, J.: Identification of a new 130 bp cis-acting element in the TsVP1 promoter involved in the salt stress response from Thellungiella halophila. - Plant Biol. 10: 90, 2010.

    Google Scholar 

  • Tester, M., Davenport, R.: Na+ tolerance and Na+ transport in higher plants. - Ann. Bot. 91: 503–527, 2003.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Tyagi, W., Rajagopal, D., Singla-Pareek, S.L., Reddy, M.K., Sopory, S.K.: Cloning and regulation of a stress-regulated Pennisetum glaucum vacuolar ATPase c gene and characterization of its promoter that is expressed in shoot hairs and floral organs. - Plant Cell Physiol. 46: 1411–1422, 2005.

    Article  PubMed  CAS  Google Scholar 

  • Vinocur, B., Altman, A.: Recent advances in engineering plant tolerance to abiotic stress, achievements and limitations. - Curr. Opin. Biotechnol. 16: 1–10, 2005.

    Article  CAS  Google Scholar 

  • Wang, R., Jing, W., Xiao, L., Jin, Y., Shen, L., Zhang, W.: The rice high-affinity potassium transporter1;1 is involved in salt tolerance and regulated by an MYB-type transcription factor. - Plant Physiol. 168: 1076–1090, 2015.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Xiong, Y., Liu. T., Tian, C., Sun, S., Li, J., Chen, M.: Transcription factors in rice. A genome-wide comparative analysis between monocots and eudicots. - Plant mol. Biol. 59: 191–203, 2005.

    Article  PubMed  CAS  Google Scholar 

  • Yadav, N.S., Shukla, P.S., Jha, A. Agarwal, P.K., Jha, B.: The SbSOS1 gene from the extreme halophyte Salicornia brachiata enhances Na+ loading in xylem and confers salt tolerance in transgenic tobacco. - BMC Plant Biol. 12: 188, 2012.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Yokoi, S., Quintero, F.J., Cubero, B. Ruiz, M.T., Bressan, R.A., Hasegawa, P.M., Pardo, J.M.: Differential expression and function of Arabidopsis thaliana NHX Na+/H+ antiporters in the salt stress response. - Plant J. 30: 529–539, 2002.

    Article  PubMed  CAS  Google Scholar 

  • Zhang, H.X., Blumwald, E.: Transgenic salt-tolerant tomato plants accumulate salt in foliage but not in fruit. - Nat. Biotechnol. 19: 765–8, 2001.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Plant Omics Division, Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research, Bhavnagar, 364002, Gujarat, India

    P. K. Agarwal, A. Dave & P. Agarwal

Authors
  1. P. K. Agarwal
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  2. A. Dave
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  3. P. Agarwal
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Correspondence to P. K. Agarwal.

Additional information

Acknowledgment: CSIR-CSMCRI Communication No. 146/2016. The authors are thankful to CSIR and DST-SERB New Delhi, India, for financial support; AD and PA are supported by CSIR-JRF and DST-WOS A fellowships, respectively.

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Agarwal, P.K., Dave, A. & Agarwal, P. Transcriptional regulation of salinity stress: role and spatio-temporal expressions of ion-transporter gene promoters. Biol Plant 62, 641–646 (2018). https://doi.org/10.1007/s10535-018-0815-2

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