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Guggulsterone production in cell suspension cultures of the guggul tree, Commiphora wightii, grown in shake-flasks and bioreactors

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Abstract

Cell suspension cultures of Commiphora wightii, grown in modified MS medium containing 2,4-dichlorophenoxyacetic acid (0.5 mg l−1) and kinetin (0.25 mg l−1), produced ∼5 μg guggulsterone g−1 dry wt. In a 2 l stirred tank bioreactor, the biomass was 5.5 g l−1 and total guggulsterone was 36 μg l−1.

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Acknowledgement

This work was supported by financial assistance (grant No. BT/PR3214/PBD/17/210/2002) from the DBT, Government of India, New Delhi, and partially by DST-FIST programme for infrastructure development and UGC-DRS under special assistance programme for medicinal plant research to KGR.

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Authors and Affiliations

  1. Laboratory of Bio-Molecular Technology, Department of Botany, M. L. Sukhadia University, Udaipur, 313001, India

    Meeta Mathur & K. G. Ramawat

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  1. Meeta Mathur
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  2. K. G. Ramawat
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Correspondence to K. G. Ramawat.

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Mathur, M., Ramawat, K.G. Guggulsterone production in cell suspension cultures of the guggul tree, Commiphora wightii, grown in shake-flasks and bioreactors. Biotechnol Lett 29, 979–982 (2007). https://doi.org/10.1007/s10529-007-9342-5

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  • DOI: https://doi.org/10.1007/s10529-007-9342-5

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