Skip to main content
SpringerLink
Log in

Iodine-Containing Coating with Prolonged Antimicrobial Activity Based on Water-Insoluble Polymer Matrix

  • Published:
Biomedical Engineering Aims and scope

UV spectroscopy demonstrated formation of a complex of iodine with vinylpyrrolidone and butyl methacrylate in nonpolar ethanol medium. This complex is soluble in alcohol and insoluble in water. Application of an alcohol solution of the complex to a wound surface results in formation of a water-impermeable film with antimicrobial properties facilitating wound healing. The antimicrobial coating lasts for 1–3 days. Use of the Iodpolycom iodine polymer coating makes it possible to abandon gauze bandages. It also reduces suppurative complications from 34 to 5% relative to control. The Iodpolycom complex is commercially available.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. V. Volenko and E. V. Kuprikov, Proc. Sci.-Pract. Conf. on Modern Battle Trauma: Actual Problems of Diagnosis and Treatment, Moscow (2001), pp. 87–88.

  2. M. D. Mashkovskii, Medicaments [in Russian], Moscow (2008).

  3. E. I. Trofimov, Prevention of Post-surgical Purulent Complications in Combined Treatment of Throat Cancer: Candidate dissertation [in Russian], Moscow (1982).

  4. M. I. Kuzin and B. M. Kostyuchenok, Wounds and Wound Infections: Manual for Physicians [in Russian], Moscow (1990).

  5. Yu. A. Davydov and A. B. Larichev, Vacuum Therapy of Wounds and Wound Process [in Russian], Moscow (1999).

  6. S. I. Belyh, A. V. Volenko, and A. B. Davydov, “A Polymer Composition for Covering Surgical and Wound Surfaces”, RF Patent No. 2 202 352.

  7. S. I. Belyh, Yu. M. Polous, and V. G. Sardak, Grudn. Khir., No. 5, 48–50 (1986).

  8. A. V. Volenko, S. I. Belyh, E. V. Firsov, et al., Med. Tekh., No. 4, 37–40 (1994).

  9. F. P. Sidel’kovskaya, Chemistry of Vinylpyrrolidon [in Russian], Nauka, Moscow (1972), pp. 2–148.

    Google Scholar 

  10. A. L. Klochkhin, A. L. Chistyakov, S. I. Belyh, et al., Proc. IV Ross. Sci. Forum Surgery 2002, Moscow (2002), pp. 107–108.

  11. G. I. Markov, A. L. Klochkhin, A. L. Chistyakov, and N. V. Chernov, Vestn. Otorinolaringol., No. 6, 349–350 (2002).

Download references

Author information

Authors and Affiliations

  1. Inpolymed V, Ltd., Moscow, Russia

    A. B. Davydov, S. I. Belyh & V. V. Kravets

Authors
  1. A. B. Davydov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. I. Belyh
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. V. Kravets
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. I. Belyh.

Additional information

Translated from Meditsinskaya Tekhnika, Vol. 46, No. 6, Nov.-Dec., 2012, pp. 18-22.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Davydov, A.B., Belyh, S.I. & Kravets, V.V. Iodine-Containing Coating with Prolonged Antimicrobial Activity Based on Water-Insoluble Polymer Matrix. Biomed Eng 46, 237–240 (2013). https://doi.org/10.1007/s10527-013-9314-0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10527-013-9314-0

Keywords

Search

Navigation