The study focuses on induction of autoantibodies directed against neurotransmitter norepinephrine during neuropathic pain syndrome and on the effect of immunization with norepinephrine-protein conjugated antigen on the development of this syndrome. The formation of anti-norepinephrine antibodies aggravated and prolonged neuropathic pain.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 12, pp. 678-681, December, 2016
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Igon’kina, S.I., Vetrile, L.A. & Kukushkin, M.L. Effect of Anti-Norepinephrine Antibodies on the Development of Neuropathic Pain. Bull Exp Biol Med 162, 714–717 (2017). https://doi.org/10.1007/s10517-017-3695-0
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DOI: https://doi.org/10.1007/s10517-017-3695-0