Antianxiety action of diterpene alkaloid songorine was studied using Vogel conflict test. Songorine in a dose of 0.25 mg/kg demonstrated high anxiolytic activity comparable to that of phenazepam and produced no sedative effect.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 5, pp. 577-579, May, 2015
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Nesterova, Y.V., Povet’eva, T.N., Suslov, N.I. et al. Anxiolytic Activity of Diterpene Alkaloid Songorine. Bull Exp Biol Med 159, 620–622 (2015). https://doi.org/10.1007/s10517-015-3029-z
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DOI: https://doi.org/10.1007/s10517-015-3029-z