We studied radiosensitivity of 101/Hf, C3H/Sn, and C57Bl mice exposed to sublethal doses of γ-radiation. C57Bl mice responded to radiation much later than 101/Hf and C3H/Sn mice, while their adaptability was high enough. 101/Hf and C3H/Sn mice developed acute radiation sickness in a similar way. However, C3H/Sn mice showed better physiological indicators after radiation crisis. There was no noticeable improvement after the development of radiation sickness in 101/Hf mice. To assess individual radiosensitivity, integrated approach should be applied using the data obtained by different methods on several physiological levels.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 2, pp. 150-153, February, 2014
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Alchinova, I.B., Arkhipova, E.N., Medvedeva, Y.S. et al. Dynamics of Changes in Physiological Parameters of Mice with Different Radiosensitivity after Acute γ-Irradiation. Bull Exp Biol Med 157, 190–193 (2014). https://doi.org/10.1007/s10517-014-2522-0
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DOI: https://doi.org/10.1007/s10517-014-2522-0