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Magnetofection of Human Somatic Cells with Magnetite and Cobalt Ferrospinel Nanoparticles

  • NANOTECHNOLOGIES
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Bulletin of Experimental Biology and Medicine Aims and scope

Superparamagnetic nanoparticles varying by their chemical composition and synthesis method were used to transfer DNA into somatic cells under the infl uence of constant magnetic field (method of magnetofection). Magnetite particles obtained by mechanochemical synthesis ensured higher expression of the marker gene GFP (evaluated by fluorescence intensity of the cell lysate) then particles of ferric oxide obtained by chemical co-precipitation and cobalt ferrospinel particles obtained by the mechanochemical method.

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Authors and Affiliations

  1. Institute of Chemical Biology and Fundumental Medicine, Siberian Division of the Russian Academy of Sciences, Siberia, Russia

    M. A. Sukoyan, E. A. Khrapov, E. N. Voronina, U. A. Boyarskikh & M. L. Filipenko

  2. A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia

    A. I. Gubanov

  3. Department of Structural Macrokinetics, Tomsk Research Center, Siberian Division of the Russian Academy of Sciences, Siberia, Russia

    V. I. Itin, A. A. Magaeva, E. P. Nayden & O. G. Terekhova

Authors
  1. M. A. Sukoyan
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  2. E. A. Khrapov
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  3. E. N. Voronina
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  4. U. A. Boyarskikh
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  5. A. I. Gubanov
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  6. V. I. Itin
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  7. A. A. Magaeva
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  8. E. P. Nayden
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  9. O. G. Terekhova
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  10. M. L. Filipenko
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Corresponding author

Correspondence to M. A. Sukoyan.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 11, pp. 633-636, November, 2012

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Sukoyan, M.A., Khrapov, E.A., Voronina, E.N. et al. Magnetofection of Human Somatic Cells with Magnetite and Cobalt Ferrospinel Nanoparticles. Bull Exp Biol Med 154, 673–676 (2013). https://doi.org/10.1007/s10517-013-2027-2

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  • DOI: https://doi.org/10.1007/s10517-013-2027-2

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